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N-钙粘附分子抗体
  • 产品货号:
    BN42189R
  • 中文名称:
    N-钙粘附分子抗体
  • 英文名称:
    Rabbit anti-N-cadherin Polyclonal antibody
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  • BN42189R-50ul

    50ul

    ¥1338.00

    交叉反应(总):Human,Mouse,Rat,Pig,Cow,Danio rerio;推荐应用:WB ELISA IHC-P IHC-F Flow-Cyt ICC IF

  • BN42189R-100ul

    100ul

    ¥2120.00

    交叉反应(总):Human,Mouse,Rat,Pig,Cow,Danio rerio;推荐应用:WB ELISA IHC-P IHC-F Flow-Cyt ICC IF

  • BN42189R-200ul

    200ul

    ¥3140.00

    交叉反应(总):Human,Mouse,Rat,Pig,Cow,Danio rerio;推荐应用:WB ELISA IHC-P IHC-F Flow-Cyt ICC IF

英文名称N-cadherin
中文名称N-钙粘附分子抗体
别    名Cadherin 2; Cadherin 2 N cadherin neuronal; Cadherin 2 type 1; Cadherin 2 type 1 N cadherin neuronal; cadherin 2 type 1 N-cadherin neuronal; Cadherin2; Calcium dependent adhesion protein neuronal; CD325; CD325 antigen; CDH2; CDHN; CDw325; CDw325 antigen; N cadherin 1; NCAD; Neural Cadherin; Neural Cadherin.  


研究领域肿瘤  细胞生物  免疫学  激酶和磷酸酶  细胞粘附分子  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Cow,  (predicted: Rat, Pig, Danio rerio)
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100 ICC=1:100 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量100kDa
细胞定位细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human N-cadherin:701-800/905 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

Function:
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.

Subcellular Location:
Cell membrane.

Similarity:
Contains 5 cadherin domains.

SWISS:
P19022

Gene ID:
1000

Database links:

Entrez Gene: 1000 Human

Entrez Gene: 281062 Cow

Entrez Gene: 12558 Mouse

Entrez Gene: 83501 Rat

Omim: 114020 Human

SwissProt: P19022 Human

SwissProt: P15116 Mouse

SwissProt: Q9Z1Y3 Rat

Unigene: 464829 Human

Unigene: 606106 Human

Unigene: 257437 Mouse

Unigene: 23200 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

细胞粘附蛋白(Call Adhesion Protein)
N-钙粘附分子属于依赖钙离子的细胞间糖蛋白粘附分子的一部分,主要是参与细胞间同源性粘附,调控和介导细胞间相互反应。


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