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BN42162R-50ul
50ul
¥2020.00
交叉反应：Human,Mouse,Rat 推荐应用：WB,IHC-P,IHC-F
BN42162R-100ul
100ul
¥3240.00
交叉反应：Human,Mouse,Rat 推荐应用：WB,IHC-P,IHC-F
| 英文名称 | CXCR5 |
| 中文名称 | 细胞表面趋化因子受体5重组兔单克隆抗体 |
| 别 名 | BLR 1; BLR1; Burkitt lymphoma receptor 1; Burkitt lymphoma receptor 1 GTP binding protein; C X C chemokine receptor type 5; C-X-C chemokine receptor type 5; CD 185; CD185; CD185 antigen; Chemokine C X C motif receptor 5; Chemokine CXC motif receptor 5; Chemokine receptor 5; CXC chemokine receptor type 5; CXC R5; CXC-R5; CXCR 5; CXCR-5; Cxcr5; CXCR5_HUMAN; MDR 15; MDR-15; MDR15; MGC117347; Monocyte derived receptor 15; Monocyte-derived receptor 15. |
| 研究领域 | 肿瘤 细胞生物 免疫学 信号转导 趋化因子 G蛋白偶联受体 b-淋巴细胞 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Monoclonal |
| 克 隆 号 | 3B7 |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | WB=1:500-1000 IHC-P=1:50-200 IHC-F=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 45kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | Recombinant human CXCR5: |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | The CXCR5 gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. CXCR5 protein is predicted to be a seven transmembrane G protein coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of the gene and its mouse conterpart strongly suggest the essential function of the protein is in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Function: Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expression in mature B-cells and Burkitt lymphoma cells. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P32302 Gene ID: 643 Database links: Entrez Gene: 643 Human Entrez Gene: 12145 Mouse Omim: 601613 Human SwissProt: P32302 Human SwissProt: Q04683 Mouse Unigene: 113916 Human Unigene: 490637 Mouse Unigene: 6246 Mouse Unigene: 120732 Rat Unigene: 127121 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
