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BN42161R-50ul
50ul
¥2020.00
交叉反应：Mouse(predicted:Rat,Human) 推荐应用：WB,IHC-P,IHC-F,ICC
BN42161R-100ul
100ul
¥3240.00
交叉反应：Mouse(predicted:Rat,Human) 推荐应用：WB,IHC-P,IHC-F,ICC
| 英文名称 | CD27 |
| 中文名称 | CD27重组兔单克隆抗体 |
| 别 名 | CD 27; Cd27; CD27 antigen; CD27 molecule; CD27_HUMAN; CD27L receptor; LPFS2; MGC20393; OTTHUMP00000238557; S152; T cell activation antigen CD27; T cell antivation antigen S152; T-cell activation antigen CD27; T14; TNFRSF 7; TNFRSF7; TNFSF7; Tp 55; Tp55; Tumor necrosis factor receptor superfamily member 7. |
| 研究领域 | 肿瘤 免疫学 干细胞 淋巴细胞 t-淋巴细胞 细胞因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Monoclonal |
| 克 隆 号 | 3C3 |
| 交叉反应 | Mouse, (predicted: Human, Rat, ) |
| 产品应用 | WB=1:500-2000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 55kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CD27: |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008] Function: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. Subunit: Homodimer. Interacts with SIVA1 and TRAF2. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Found in most T-lymphocytes. Post-translational modifications: Phosphorylated. O-glycosylated with core 1 or possibly core 8 glycans. Similarity: Contains 3 TNFR-Cys repeats. SWISS: P26842 Gene ID: 939 Database links: Entrez Gene: 939 Human Entrez Gene: 21940 Mouse Omim: 186711 Human SwissProt: P26842 Human SwissProt: P41272 Mouse Unigene: 355307 Human Unigene: 367714 Mouse Unigene: 134200 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
