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神经元核抗原重组兔单克隆抗体
  • 产品货号：
    BN42120R
  • 中文名称：
    神经元核抗原重组兔单克隆抗体
  • 英文名称：
    Rabbit anti-NeuN Monoclonal antibody

  • 货号

    产品规格

    售价

    备注

  • BN42120R-50ul

    50ul

    ¥2020.00

    交叉反应：Rat,Mouse,Human 推荐应用：WB,IHC-P,IHC-F

  • BN42120R-100ul

    100ul

    ¥3240.00

    交叉反应：Rat,Mouse,Human 推荐应用：WB,IHC-P,IHC-F

英文名称NeuN
中文名称神经元核抗原重组兔单克隆抗体
别    名FOX3; NeuN; neuronal nuclei antigen; neuronal nuclei; Vertebrate neuron-specific nuclear protein; Neuna60; Neuronal nuclear antigen A60; RNA binding protein fox-1 homolog 3 isoform 1; RNA binding protein, fox 1 homolog (C. elegans) 3; Rbfox3; D11Bwg0517e; Fox-3; Fox3; Hrnbp3; RP23-159O6.5; novel protein; Fox-1 homolog C; fox1 homolog C; FLJ56884; FLJ58356; hexaribonucleotide binding protein 3 RFOX3_HUMAN.  
研究领域细胞生物  神经生物学  转运蛋白  表观遗传学  
抗体来源Rabbit
克隆类型Monoclonal
克 隆 号12C3
交叉反应Mouse, Rat,  (predicted: Human, )
产品应用WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量34kDa
细胞定位细胞核 细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human NeuN: 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Vertebrate neuron-specific nuclear protein called NeuN (Neuronal Nuclei) is an excellent marker for neurons in primary cultures and in retinoic acid-stimulated P19 cells. It is also useful for identifying neurons in transplants. NeuN is a neuron-specific, DNA-binding nuclear protein in vertebrates. In mice, NeuN is observed in most neuronal cell types throughout the nervous system, including cerebellum, cerebral cortex, hippocampus, thalamus and spinal cord, as well as the dorsal root ganglia, sympathetic chain ganglia and enteric ganglia of the peripheral nervous system. NeuN immunoreactivity is first observed in neurons when they become post-mitotic and are initiating cellular and morphological differentiation. No staining is observed in proliferative zones. NeuN has been used as an immunohistochemical marker for excitotoxic lesions of the brain as well as in the diagnosis of a wide range of human tissue specimens from the central and peripheral nervous systems.

Function:
RNA-binding protein that regulates alternative splicing events.

Subcellular Location:
Nucleus. Cytoplasm.

Similarity:
Contains 1 RRM (RNA recognition motif) domain.

SWISS:
A6NFN3

Gene ID:
146713

Database links:

Entrez Gene: 146713 Human

Entrez Gene: 52897 Mouse

Entrez Gene: 287847 Rat

SwissProt: A6NFN3 Human

SwissProt: Q8BIF2 Mouse

Unigene: 135229 Human

Unigene: 341103 Mouse

Unigene: 143966 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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