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促进调解蛋白家族2A抗体
  • 产品货号:
    BN41934R
  • 中文名称:
    促进调解蛋白家族2A抗体
  • 英文名称:
    Rabbit anti-MFSD2A Polyclonal antibody
  • 货号

    产品规格

    售价

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  • BN41934R-50ul

    50ul

    ¥1486.00

    交叉反应:Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41934R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41934R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

英文名称MFSD2A
中文名称促进调解蛋白家族2A抗体
别    名Major facilitator superfamily domain containing 2; Major facilitator superfamily domain containing 2A; Major facilitator superfamily domain-containing protein 2A; MFS2A_HUMAN; MFSD2; MFSD2A.


研究领域肿瘤  神经生物学  信号转导  转录调节因子  G蛋白偶联受体  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2ug/test IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量60kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human MFSD2A:331-430/543 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍MFSD2 is a 543 amino acid multi-pass membrane protein of the endoplasmic reticulum that is involved in beta-adrenergic signaling during thermogenesis. Existing as three alternatively spliced isoforms, MFSD2 plays a role in G1 regulation and is encoded by a gene that maps to human chromosome 1p34.2. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.

Function:
Play a role in thermogenesis via beta-adrenergic signaling pathway.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:


Similarity:
Belongs to the major facilitator superfamily.

SWISS:
Q8NA29

Gene ID:
84879

Database links:

Entrez Gene: 84879 Human

Entrez Gene: 76574 Mouse

Entrez Gene: 298504 Rat

Omim: 614397 Human

SwissProt: Q8NA29 Human

SwissProt: Q9DA75 Mouse

Unigene: 655177 Human

Unigene: 331842 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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