货号
产品规格
售价
备注
BN41932R-50ul
50ul
¥1486.00
交叉反应：Human,Rat(predicted:Mouse) 推荐应用：IHC-P,IHC-F,IF,ELISA
BN41932R-100ul
100ul
¥2360.00
交叉反应：Human,Rat(predicted:Mouse) 推荐应用：IHC-P,IHC-F,IF,ELISA
BN41932R-200ul
200ul
¥3490.00
交叉反应：Human,Rat(predicted:Mouse) 推荐应用：IHC-P,IHC-F,IF,ELISA
| 英文名称 | CD200 |
| 中文名称 | 膜糖蛋白CD200抗体 |
| 别 名 | CD200; CD200 antigen; CD200 molecule; MOX1; MOX2; MRC; MRC OX 2 antigen; My033; OX 2; OX 2 membrane glycoprotein precursor; OX-2 membrane glycoprotein; OX2G; OX2G_HUMAN. |
| 研究领域 | 细胞生物 免疫学 细胞表面分子 糖蛋白 淋巴细胞 t-淋巴细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, (predicted: Mouse, Rat, ) |
| 产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 28kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CD200:41-140/278 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] Function: Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. Subunit: Interacts with CD200R1. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain. SWISS: P41217 Gene ID: 4345 Database links: Entrez Gene: 4345 Human Omim: 155970 Human SwissProt: P41217 Human Unigene: 79015 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CD200是Ⅰ型膜糖蛋白，为免疫球蛋白超家族的新成员，广泛表达在人类胸腺细胞、B细胞、激活的T细胞、滤泡状树突细胞、神经元及血管内皮上。可表达于B细胞及其增殖性疾病和一部分T细胞。近年来研究发现，CD200与CD200R间的相互作用可以传递抑制性信号减低髓样细胞的活性，改变其迁移。CD200在免疫疾病和抑制排斥反应中作为一种免疫耐受信号，它的一些相关分子在免疫调节中也具有一定的作用。 |
