首页>>蛋白研究>>抗体>>去整合素样金属蛋白酶23抗体
去整合素样金属蛋白酶23抗体
  • 产品货号:
    BN41926R
  • 中文名称:
    去整合素样金属蛋白酶23抗体
  • 英文名称:
    Rabbit anti-ADAM23 Polyclonal antibody
  • 货号

    产品规格

    售价

    备注

  • BN41926R-50ul

    50ul

    ¥1486.00

    交叉反应:Human,Mouse,Rat(predicted:Pig,Cow,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41926R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse,Rat(predicted:Pig,Cow,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41926R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse,Rat(predicted:Pig,Cow,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

英文名称ADAM23
中文名称去整合素样金属蛋白酶23抗体
别    名A disintegrin and metalloproteinase domain 23; MDC 3; Metalloproteinase like disintegrin like and cysteine rich protein 3.  
研究领域肿瘤  细胞生物  免疫学  信号转导  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse,  (predicted: Rat, Pig, Cow, Horse, Rabbit, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2ug/Test IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量75-95kDa
细胞定位细胞膜 分泌型蛋白 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ADAM23:551-650/832 <Extracellular>
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍ADAM23 is a non-catalytic metalloprotease-like protein. It is highly expressed in the brain, primarily in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole, and weakly expressed in the heart. 3 isoforms are produced by alternative splicing, alpha, beta and gamma. ADAM23 may play a role in cell-cell and cell-matrix interactions.

Subunit:
Can bind to LGI1 and LGI4 (By similarity). Ligand for integrin alpha-V/beta-3.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Isoform Gamma: Secreted.

Tissue Specificity:
Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole.

Similarity:
Contains 1 disintegrin domain.
Contains 1 EGF-like domain.
Contains 1 peptidase M12B domain.

SWISS:
O75077

Gene ID:
8745

Database links:

Entrez Gene: 8745 Human

Entrez Gene: 23792 Mouse

Entrez Gene: 301460 Rat

Omim: 603710 Human

SwissProt: O75077 Human

SwissProt: Q9R1V7 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

细胞外基质蛋白


image.png

image.png

image.png