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乳铁蛋白抗体
  • 产品货号:
    BN41925R
  • 中文名称:
    乳铁蛋白抗体
  • 英文名称:
    Rabbit anti-Lactoferrin Polyclonal antibody
  • 货号

    产品规格

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  • BN41925R-50ul

    50ul

    ¥1486.00

    交叉反应:Human(predicted:Sheep,Horse,Cow,Pig,Dog,Rat,Mouse) 推荐应用:WB,Flow-Cyt,ELISA

  • BN41925R-100ul

    100ul

    ¥2360.00

    交叉反应:Human(predicted:Sheep,Horse,Cow,Pig,Dog,Rat,Mouse) 推荐应用:WB,Flow-Cyt,ELISA

  • BN41925R-200ul

    200ul

    ¥3490.00

    交叉反应:Human(predicted:Sheep,Horse,Cow,Pig,Dog,Rat,Mouse) 推荐应用:WB,Flow-Cyt,ELISA

英文名称Lactoferrin
中文名称乳铁蛋白抗体
别    名CKRX; GIG12; Growth inhibiting protein 12; HLF2; Homo sapiens chemokine receptor X; Kaliocin 1; Lactoferrin; Lactoferroxin A; Lactoferroxin B; Lactoferroxin C; Lactoferroxin-C; Lactotransferrin; LF; LTF; Neutrophil lactoferrin; Talalactoferrin alfa; Talalactoferrin; TRFL_HUMAN.  


研究领域肿瘤  心血管  细胞生物  免疫学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=0.2ug/test 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量76kDa
细胞定位细胞核 细胞浆 分泌型蛋白 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Lactoferrin:611-710/710 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.

Function:
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.
Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration.
Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors.
The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.
Isoform DeltaLf: transcription factor with antiproliferative properties and inducing cell cycle arrest. Binds to DeltaLf response element found in the SKP1, BAX, DCPS, and SELH promoters.

Subunit:
Monomer. Found in a complex with LTF, CLU, EPPIN and SEMG1.

Subcellular Location:
Isoform 1: Secreted. Isoform DeltaLf: Cytoplasm. Nucleus.

Post-translational modifications:
Isoform DeltaLf: Ubiquitinated at Lys-379 and Lys-391.

Similarity:
Belongs to the transferrin family.
Contains 2 transferrin-like domains.

SWISS:
P02788

Gene ID:
4057

Database links:

Entrez Gene: 4057 Human

Entrez Gene: 17002 Mouse

Entrez Gene: 301034 Rat

Omim: 150210 Human

SwissProt: P02788 Human

SwissProt: P08071 Mouse

Unigene: 529517 Human

Unigene: 282359 Mouse

Unigene: 218647 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applicati

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