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单核细胞趋化诱导蛋白1抗体
  • 产品货号：
    BN41924R
  • 中文名称：
    单核细胞趋化诱导蛋白1抗体
  • 英文名称：
    Rabbit anti-MCPIP1 Polyclonal antibody

  • 货号

    产品规格

    售价

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  • BN41924R-50ul

    50ul

    ¥1486.00

    交叉反应：Human,Mouse(predicted:Rat,Chicken,Dog,Cow,Horse,Rabbit) 推荐应用：WB,IF,Flow-Cyt,ELISA

  • BN41924R-100ul

    100ul

    ¥2360.00

    交叉反应：Human,Mouse(predicted:Rat,Chicken,Dog,Cow,Horse,Rabbit) 推荐应用：WB,IF,Flow-Cyt,ELISA

  • BN41924R-200ul

    200ul

    ¥3490.00

    交叉反应：Human,Mouse(predicted:Rat,Chicken,Dog,Cow,Horse,Rabbit) 推荐应用：WB,IF,Flow-Cyt,ELISA

英文名称MCPIP1
中文名称单核细胞趋化诱导蛋白1抗体
别    名dJ423B22.1; MCP 1 treatment-induced protein; MCP-induced protein 1; MCPIP 1; MCPIP; Ribonuclease ZC3H12A; RP3-423B22.1; ZC12A_HUMAN; ZC3H 12A; ZC3H12 A; Zc3h12a; Zinc finger CCCH domain-containing protein 12A; Zinc finger CCCH type containing 12A.  
研究领域肿瘤  心血管  细胞生物  免疫学  染色质和核信号  信号转导  细胞凋亡  转录调节因子  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse,  (predicted: Rat, Chicken, Dog, Cow, Horse, Rabbit, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量66kDa
细胞定位细胞核 细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human MCPIP1:201-300/599 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19.

Function:
Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19.

Subcellular Location:
Cytoplasm. Nucleus.

Similarity:
Belongs to the ZC3H12 family.
Contains 1 C3H1-type zinc finger.

SWISS:
Q5D1E8

Gene ID:
80149

Database links:

Entrez Gene: 535344 Cow

Entrez Gene: 80149 Human

Entrez Gene: 230738 Mouse

Omim: 610562 Human

SwissProt: A6QQJ8 Cow

SwissProt: Q5D1E8 Human

SwissProt: Q5D1E7 Mouse

Unigene: 656294 Human

Unigene: 402 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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