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跨膜蛋白16A/钙激活氯离子通道抗体
  • 产品货号:
    BN41876R
  • 中文名称:
    跨膜蛋白16A/钙激活氯离子通道抗体
  • 英文名称:
    Rabbit anti-ANO1/TMEM16A Polyclonal antibody
  • 货号

    产品规格

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  • BN41876R-50ul

    50ul

    ¥1486.00

    交叉反应:Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

  • BN41876R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

  • BN41876R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

英文名称ANO1/TMEM16A
中文名称跨膜蛋白16A/钙激活氯离子通道抗体
别    名ANO 1;ANO1_HUMAN; Anoctamin 1; Anoctamin 1 calcium activated chloride channel; Anoctamin-1; Anoctamin1; Discovered on gastrointestinal stromal tumors protein 1; DOG 1; FLJ10261; Membrane protein; Oral cancer overexpressed 2; Oral cancer overexpressed protein 2; ORAOV 2; ORAOV2; TAOS 2; TAOS2; TMEM 16A; TMEM16A; Transmembrane protein 16A (eight membrane spanning domains); Transmembrane protein 16A; Tumor amplified and overexpressed sequence 2; Tumor-amplified and overexpressed sequence 2.  
研究领域肿瘤  细胞生物  免疫学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量114kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human DOG-1/TMEM16A:151-250/986 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍TMEM16A (Transmembrane protein 16A) is an eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products and is amplified in various cancers. It acts as a calcium-activated chloride channel and is required for normal tracheal development.

Function:
Acts as a calcium-activated chloride channel. Required for normal tracheal development (By similarity).

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cytoplasm.

Tissue Specificity:
Broadly expressed with higher levels in liver and skeletal muscle.

Similarity:
Belongs to the anoctamin family.

SWISS:
Q5XXA6

Gene ID:
55107

Database links:

Entrez Gene: 55107 Human

Entrez Gene: 101772 Mouse

Entrez Gene: 309135 Rat

Omim: 610108 Human

SwissProt: Q5XXA6 Human

SwissProt: Q8BHY3 Mouse

Unigene: 503074 Human

Unigene: 26700 Mouse

Unigene: 162509 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications


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