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肺Kruppel样因子抗体
  • 产品货号:
    BN41849R
  • 中文名称:
    肺Kruppel样因子抗体
  • 英文名称:
    Rabbit anti-KLF2 Polyclonal antibody
  • 货号

    产品规格

    售价

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  • BN41849R-50ul

    50ul

    ¥1486.00

    交叉反应:Human,Mouse,Rat(predicted:Pig,Cow,Horse,Rabbit,Sheep) 推荐应用:WB,IHC-P,IHC-F,IF,Flow-Cyt

  • BN41849R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse,Rat(predicted:Pig,Cow,Horse,Rabbit,Sheep) 推荐应用:WB,IHC-P,IHC-F,IF,Flow-Cyt

  • BN41849R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse,Rat(predicted:Pig,Cow,Horse,Rabbit,Sheep) 推荐应用:WB,IHC-P,IHC-F,IF,Flow-Cyt

英文名称KLF2
中文名称肺Kruppel样因子抗体
别    名Kruppel like factor 2; Kruppel like factor; Kruppel like factor LKLF; Kruppel-like factor 2 (lung); Lung krueppel like factor; Lung Kruppel like zinc finger transcription factor; KLF 2; Klf2; KLF2_HUMAN; Krueppel-like factor 2; Lklf; Lung krueppel like factor; Lung krueppel-like factor; Lung Kruppel like zinc finger transcription factor.  


研究领域肿瘤  细胞生物  信号转导  转录调节因子  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,  (predicted: Pig, Cow, Horse, Rabbit, Sheep, )
产品应用WB=1:100-500 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:ug/Test IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量37kDa
细胞定位细胞核 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human KLF2:251-355/355 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011]

Function:
Binds to the CACCC box in the beta-globin gene promoter and activates transcription .

Subunit:
Interacts with WWP1.

Subcellular Location:
Nucleus.

Post-translational modifications:
Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 3 C2H2-type zinc fingers.

SWISS:
Q9Y5W3

Gene ID:
10365

Database links:

Entrez Gene: 10365 Human

Entrez Gene: 16598 Mouse

Entrez Gene: 306330 Rat

Omim: 602016 Human

SwissProt: Q9Y5W3 Human

SwissProt: Q60843 Mouse

SwissProt: Q9ET58 Rat

Unigene: 107740 Human

Unigene: 726356 Human

Unigene: 26938 Mouse

Unigene: 92653 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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