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CD30抗体
  • 产品货号：
    BN41826R
  • 中文名称：
    CD30抗体
  • 英文名称：
    Rabbit anti-CD30 Polyclonal antibody

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    产品规格

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  • BN41826R-50ul

    50ul

    ¥1486.00

    交叉反应：Human,Pig(predicted:Rabbit) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41826R-100ul

    100ul

    ¥2360.00

    交叉反应：Human,Pig(predicted:Rabbit) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN41826R-200ul

    200ul

    ¥3490.00

    交叉反应：Human,Pig(predicted:Rabbit) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

英文名称CD30
中文名称CD30抗体
别    名CD 30; CD30; CD30 antigen; CD30L receptor; Cytokine receptor CD30; D1S166E; KI 1; Ki 1 antigen; Ki-1 antigen; KI1; Lymphocyte activation antigen CD30; TNFRSF 8; TNFRSF8; TNFRSF8; TNR8_HUMAN; Tumor Necrosis Factor Receptor Superfamily Member 8; Tumor Necrosis Factor Receptor Superfamily Member 8.  


研究领域肿瘤  免疫学  细胞类型标志物  肿瘤细胞生物标志物  细胞因子  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Pig,  (predicted: Rabbit, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2μg/Test IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量62kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human CD30:131-230/595 <Extracellular>
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Function:
Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.

Subunit:
Interacts with TRAF1, TRAF2, TRAF3 and TRAF5.

Subcellular Location:
Isoform Long: Cell membrane; Single-pass type I membrane protein.
Isoform Short: Cytoplasm.

Post-translational modifications:
Phosphorylated on serine and tyrosine residues.

Similarity:
Contains 6 TNFR-Cys repeats.

SWISS:
P28908

Gene ID:
943

Database links:

Entrez Gene: 943 Human

Omim: 153243 Human

SwissProt: P28908 Human

Unigene: 1314 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD30是一种单链糖蛋白，标记活化T和B淋巴细胞，R-S细胞和部分淋巴滤泡间区免疫母细胞。CD30是霍奇金淋巴瘤的一个特异性标记，也是大细胞间变型淋巴瘤的诊断型标志。

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