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CD27抗体
  • 产品货号：
    BN41825R
  • 中文名称：
    CD27抗体
  • 英文名称：
    Rabbit anti-CD27 Polyclonal antibody

  • 货号

    产品规格

    售价

    备注

  • BN41825R-50ul

    50ul

    ¥1486.00

    交叉反应：Mouse,Rat(predicted:Human,Dog,Pig,Cow) 推荐应用：WB,ELISA

  • BN41825R-100ul

    100ul

    ¥2360.00

    交叉反应：Mouse,Rat(predicted:Human,Dog,Pig,Cow) 推荐应用：WB,ELISA

  • BN41825R-200ul

    200ul

    ¥3490.00

    交叉反应：Mouse,Rat(predicted:Human,Dog,Pig,Cow) 推荐应用：WB,ELISA

英文名称CD27
中文名称CD27抗体
别    名CD 27; Cd27; CD27 antigen; CD27 molecule; CD27_HUMAN; CD27L receptor; LPFS2; MGC20393; OTTHUMP00000238557; S152; T cell activation antigen CD27; T cell antivation antigen S152; T-cell activation antigen CD27; T14; TNFRSF 7; TNFRSF7; TNFSF7; Tp 55; Tp55; Tumor necrosis factor receptor superfamily member 7.  



研究领域肿瘤  免疫学 干细胞  淋巴细胞  t-淋巴细胞  细胞因子  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量27kDa
细胞定位细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human CD27:201-260/260 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

Function:
Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.

Subunit:
Homodimer. Interacts with SIVA1 and TRAF2.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Found in most T-lymphocytes.

Post-translational modifications:
Phosphorylated.
O-glycosylated with core 1 or possibly core 8 glycans.

Similarity:
Contains 3 TNFR-Cys repeats.

SWISS:
P26842

Gene ID:
939

Database links:

Entrez Gene: 939 Human

Entrez Gene: 21940 Mouse

Entrez Gene: 500318 Rat

Omim: 186711 Human

SwissProt: P26842 Human

SwissProt: P41272 Mouse

Unigene: 355307 Human

Unigene: 367714 Mouse

Unigene: 134200 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.















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