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细胞衰老抑制基因抗体
  • 产品货号：
    BN41805R
  • 中文名称：
    细胞衰老抑制基因抗体
  • 英文名称：
    Rabbit anti-RSL1D1 Polyclonal antibody

  • 货号

    产品规格

    售价

    备注

  • BN41805R-50ul

    50ul

    ¥1486.00

    交叉反应：Mouse,Rat 推荐应用：WB,IHC-P

  • BN41805R-100ul

    100ul

    ¥2360.00

    交叉反应：Mouse,Rat 推荐应用：WB,IHC-P

  • BN41805R-200ul

    200ul

    ¥3490.00

    交叉反应：Mouse,Rat 推荐应用：WB,IHC-P

英文名称RSL1D1
中文名称细胞衰老抑制基因抗体
别    名CATX 11; CATX-11; CATX11; Cellular senescence inhibited gene protein; L12; PBK1; CSIG; L12; PBK1; Protein PBK1; Ribosomal L1 domain-containing protein 1; RL1D1_HUMAN; Ribosomal L1 domain containing 1.  
研究领域肿瘤  染色质和核信号  信号转导  细胞周期蛋白  转录调节因子  细胞分化  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat, 
产品应用WB=1:500-2000 IHC-P=1:400-800 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量55kDa
细胞定位细胞核 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from mouse RSL1D1:311-410/452 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍RSL1D1, also known as CATX-11, PBK1, L12 or CSIG, is a 490 amino acid nuclear protein that belongs to the ribosomal protein L1P family. Expressed in placenta, RSL1D1 contains many phosphorylated amino acid residues and is encoded by a gene that maps to human chromosome 16p13.13. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias.

Subcellular Location:
Nucleus, nucleolus.

Tissue Specificity:
Placenta.

Similarity:
Belongs to the ribosomal protein L1P family. Highly divergent.

SWISS:
Q8BVY0

Gene ID:
66409

Database links:

Entrez Gene: 26156 Human

SwissProt: O76021 Human

Unigene: 401842 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CSIG可抑制细胞衰老并延长细胞寿命 ,可能通过核糖体生物合成过程或基因转录调节来调控细胞衰老过程.














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