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胰岛素样生长因子结合蛋白3抗体
  • 产品货号：
    BN41801R
  • 中文名称：
    胰岛素样生长因子结合蛋白3抗体
  • 英文名称：
    Rabbit anti-IGFBP3 Polyclonal antibody

  • 货号

    产品规格

    售价

    备注

  • BN41801R-50ul

    50ul

    ¥1486.00

    交叉反应：Rat,Mouse(predicted:Sheep,Horse,Cow,Pig,Human) 推荐应用：WB

  • BN41801R-100ul

    100ul

    ¥2360.00

    交叉反应：Rat,Mouse(predicted:Sheep,Horse,Cow,Pig,Human) 推荐应用：WB

  • BN41801R-200ul

    200ul

    ¥3490.00

    交叉反应：Rat,Mouse(predicted:Sheep,Horse,Cow,Pig,Human) 推荐应用：WB

英文名称IGFBP3
中文名称胰岛素样生长因子结合蛋白3抗体
别    名IGF BP3; IGF-BP3; Acid stable subunit of the 140 K IGF complex; Binding protein 29; Binding protein 53; BP 53; BP53; Growth hormone dependent binding protein; IBP 3; IBP3; IGF binding protein 3; IGFBP 3;IGFBP-3; Insulin Like Growth Factor Binding Protein 3; IBP3_HUMAN.  
研究领域肿瘤  细胞生物  免疫学  生长因子和激素  糖尿病  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Rat,  (predicted: Mouse, Pig, Cow, Horse, Sheep, )
产品应用WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量32kDa
细胞定位分泌型蛋白 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human IGFBP3:131-231/292 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍GFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed by most tissues. Present in plasma.

Post-translational modifications:
Phosphorylation sites are present in the extracelllular medium.

Similarity:
Contains 1 IGFBP N-terminal domain.
Contains 1 thyroglobulin type-1 domain.

SWISS:
P17936

Gene ID:
3486

Database links:

Entrez Gene: 3486 Human

Entrez Gene: 16009 Mouse

Entrez Gene: 24484 Rat

Omim: 146732 Human

SwissProt: P17936 Human

SwissProt: P47878 Mouse

SwissProt: P15473 Rat

Unigene: 450230 Human

Unigene: 697535 Human

Unigene: 29254 Mouse

Unigene: 26369 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.











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