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BN41796R-50ul
50ul
¥1486.00
交叉反应:Mouse,Rat(predicted:Human) 推荐应用:WB,IHC-P,IHC-F,ICC,IF
BN41796R-100ul
100ul
¥2360.00
交叉反应:Mouse,Rat(predicted:Human) 推荐应用:WB,IHC-P,IHC-F,ICC,IF
BN41796R-200ul
200ul
¥3490.00
交叉反应:Mouse,Rat(predicted:Human) 推荐应用:WB,IHC-P,IHC-F,ICC,IF
英文名称 | Nur77 |
中文名称 | 孤儿核受体蛋白Nur77抗体 |
别 名 | GFRP 1; GFRP; GFRP1; Growth factor inducible nuclear protein N10; Growth Factor Inducible Nuclear Protein NP10; Growth Factor Response Protein 1; Hbr1; HMR; Hormone Receptor; MGC9485; N10; N10 nuclear protein; NAK 1; NAK1; NGFIB; NP 10; NP10; NR4A1; Nuclear hormone receptor NUR/77; Nuclear Hormone Receptor TR3; Nuclear Receptor Subfamily 4 Group A Member 1; NUR77; Orphan nuclear receptor HMR; Orphan nuclear receptor NR4A1; ST 59; ST59; Steroid receptor TR3; TR 3; TR3; TR3 orphan receptor; Early response protein NAK1. |
研究领域 | 肿瘤 细胞生物 免疫学 染色质和核信号 神经生物学 信号转导 细胞凋亡 转录调节因子 糖尿病 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Mouse, Rat, (predicted: Human, ) |
产品应用 | WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 66kDa |
细胞定位 | 细胞核 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Nur77:101-200/598 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
产品介绍 | This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011] Subunit: Binds DNA as a monomer (By similarity). Interacts with GADD45GIP1. Subcellular Location: Nucleus. Tissue Specificity: Fetal muscle and adult liver, brain and thyroid. Similarity: Belongs to the nuclear hormone receptor family. NR4 subfamily. Contains 1 nuclear receptor DNA-binding domain. SWISS: P22736 Gene ID: 3164 Database links: Entrez Gene: 3164 Human Entrez Gene: 15370 Mouse Omim: 139139 Human SwissProt: P22736 Human SwissProt: P12813 Mouse Unigene: 524430 Human Unigene: 119 Mouse Unigene: 10000 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |