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细胞骨架相关蛋白抗体
  • 产品货号:
    BN41788R
  • 中文名称:
    细胞骨架相关蛋白抗体
  • 英文名称:
    Rabbit anti-SM22 Alpha Polyclonal antibody
  • 货号

    产品规格

    售价

    备注

  • BN41788R-50ul

    50ul

    ¥1486.00

    交叉反应:Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) 推荐应用:IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN41788R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) 推荐应用:IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN41788R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) 推荐应用:IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

英文名称SM22 Alpha
中文名称细胞骨架相关蛋白抗体
别    名22 kDa actin binding protein; 22 kDa actin-binding protein; Transgelin; DKFZp686P11128; Human 22kDa smooth muscle protein; Protein WS3-10; SM22 alpha; SM22; SM22-alpha; SMCC; Smooth muscle protein 22-alpha; TAGL_HUMAN; TAGLN; TAGLN1; transgelin; Transgelin variant 2; WS3 10; Protein WS3-10; WS3-10.  
研究领域心血管  细胞生物  信号转导  细胞骨架  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
产品应用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test ICC= IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量22kDa
细胞定位细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human SM22 Alpha:101-201/201 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Actin cross-linking/gelling protein. Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence.

Subcellular Location:
Cytoplasm (Probable).

Similarity:
Belongs to the calponin family.
Contains 1 calponin-like repeat.
Contains 1 CH (calponin-homology) domain.

SWISS:
Q01995

Gene ID:
6876

Database links:

Entrez Gene: 513463 Cow

Entrez Gene: 6876 Human

Entrez Gene: 8407 Human

Entrez Gene: 21345 Mouse

Entrez Gene: 25123 Rat

Omim: 600818 Human

SwissProt: Q9TS87 Cow

SwissProt: Q01995 Human

SwissProt: P37804 Mouse

SwissProt: P31232 Rat

Unigene: 410977 Human

Unigene: 666842 Human

Unigene: 283283 Mouse

Unigene: 34397 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

SM22α蛋白是一种细胞骨架相关蛋白.












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