货号
产品规格
售价
备注
BN41783R-50ul
50ul
¥1486.00
交叉反应:Human,Mouse,Rat(predicted:Chicken,Dog,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA
BN41783R-100ul
100ul
¥2360.00
交叉反应:Human,Mouse,Rat(predicted:Chicken,Dog,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA
BN41783R-200ul
200ul
¥3490.00
交叉反应:Human,Mouse,Rat(predicted:Chicken,Dog,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA
英文名称 | Apelin Receptor |
中文名称 | 血管紧张素II受体样蛋白1抗体 |
别 名 | APJ receptor; AGTR L1; AGTRL 1; AGTRL1; Angiotensin II receptor like 1; Angiotensin receptor like 1; Apelin receptor; APJ; B78; FLJ90771; G protein coupled receptor APJ; GPCR34; HG 11; HG11; MGC45246; MSR; msr/apj; Aplnr; Agtrl1; APLNR; FLJ96609; APJ_HUMAN. |
研究领域 | 心血管 细胞生物 免疫学 G蛋白偶联受体 G蛋白信号 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, (predicted: Chicken, Dog, Horse, Rabbit, ) |
产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 42kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Apelin Receptor :181-280/380 <Cytoplasmic> |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
产品介绍 | This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq Function: Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia. Subcellular Location: Cell membrane. Tissue Specificity: Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P35414 Gene ID: 187 Database links: Entrez Gene: 429337 Chicken Entrez Gene: 187 Human Entrez Gene: 23796 Mouse Omim: 600052 Human SwissProt: P35414 Human SwissProt: Q9WV08 Mouse Unigene: 438311 Human Unigene: 29368 Mouse Unigene: 7965 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |