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血管紧张素II受体样蛋白1抗体
  • 产品货号:
    BN41783R
  • 中文名称:
    血管紧张素II受体样蛋白1抗体
  • 英文名称:
    Rabbit anti-Apelin Receptor Polyclonal antibody
  • 货号

    产品规格

    售价

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  • BN41783R-50ul

    50ul

    ¥1486.00

    交叉反应:Human,Mouse,Rat(predicted:Chicken,Dog,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN41783R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse,Rat(predicted:Chicken,Dog,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN41783R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse,Rat(predicted:Chicken,Dog,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

英文名称Apelin Receptor
中文名称血管紧张素II受体样蛋白1抗体
别    名APJ receptor; AGTR L1; AGTRL 1; AGTRL1; Angiotensin II receptor like 1; Angiotensin receptor like 1; Apelin receptor; APJ; B78; FLJ90771; G protein coupled receptor APJ; GPCR34; HG 11; HG11; MGC45246; MSR; msr/apj; Aplnr; Agtrl1; APLNR; FLJ96609; APJ_HUMAN.  
研究领域心血管  细胞生物  免疫学  G蛋白偶联受体  G蛋白信号  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,  (predicted: Chicken, Dog, Horse, Rabbit, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量42kDa
细胞定位细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Apelin Receptor :181-280/380 <Cytoplasmic>
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq

Function:
Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P35414

Gene ID:
187

Database links:

Entrez Gene: 429337 Chicken

Entrez Gene: 615435 Cow

Entrez Gene: 187 Human

Entrez Gene: 23796 Mouse

Entrez Gene: 83518 Rat

Omim: 600052 Human

SwissProt: P35414 Human

SwissProt: Q9WV08 Mouse

SwissProt: Q9JHG3 Rat

Unigene: 438311 Human

Unigene: 29368 Mouse

Unigene: 7965 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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