货号
产品规格
售价
备注
BN41781R-50ul
50ul
¥1486.00
交叉反应：Human,Mouse,Rat(predicted:Chicken,Cow) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41781R-100ul
100ul
¥2360.00
交叉反应：Human,Mouse,Rat(predicted:Chicken,Cow) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41781R-200ul
200ul
¥3490.00
交叉反应：Human,Mouse,Rat(predicted:Chicken,Cow) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
| 英文名称 | 5HT4 Receptor |
| 中文名称 | 5-羟色胺受体4抗体 |
| 别 名 | 5-HTR4 (5-hydroxytryptamine (serotonin) receptor 4a); Htr4a; 5-HT4; 5-HT4A; 5HT4; Htr45 HT 4; 5 HT4; 5 HT4R; 5 hydroxytryptamine 4 receptor; 5 hydroxytryptamine receptor 4; 5 hydroxytryptamine serotonin receptor 4; 5 hydroxytryptamine4 receptor; 5HT4; 5HT4R; Cardiac 5 HT4 receptor; HTR 4; HTR4; Serotonin 5 HT4 receptor; Serotonin receptor 4; 5HT4R_HUMAN. |
| 研究领域 | 神经生物学 信号转导 通道蛋白 细胞膜受体 转运蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, Rat, (predicted: Human, Chicken, Cow, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:200-800 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 43kDa |
| 细胞定位 | 细胞浆 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human 5-HTR4:21-120/388 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010] Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. Subunit: Isoform 5-HT4(A) interacts with MAGI2, MPP3, SLC9A3R1 and SNX27 isoforms 1 and 2. Isoform 5-HT4(E) interacts with INADL, NOS1 and SEC23A. Isoform 5-HT4(A) forms a complex including SLC9A3R1 and EZR. Subcellular Location: Cell membrane; Multi-pass membrane protein. Endosome. Note=Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli. Tissue Specificity: soform 5-HT4(A) is expressed in ileum, brain, and atrium, but not in the ventricle. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: Q13639 Gene ID: 3360 Database links: Entrez Gene: 3360 Human Entrez Gene: 15562 Mouse GenBank: NP_000861.1 Human Omim: 602164 Human SwissProt: O70528 Guinea pig SwissProt: Q13639 Human SwissProt: P97288 Mouse Unigene: 483773 Human Unigene: 20440 Mouse Unigene: 10094 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
