首页>>蛋白研究>>抗体>>胶质细胞谷氨酸运载蛋白3/神经/上皮细胞谷氨酸运载蛋白抗体
胶质细胞谷氨酸运载蛋白3/神经/上皮细胞谷氨酸运载蛋白抗体
  • 产品货号：
    BN41748R
  • 中文名称：
    胶质细胞谷氨酸运载蛋白3/神经/上皮细胞谷氨酸运载蛋白抗体
  • 英文名称：
    Rabbit anti-EAAT3 Polyclonal antibody

  • 货号

    产品规格

    售价

    备注

  • BN41748R-50ul

    50ul

    ¥1486.00

    交叉反应：Human,Mouse(predicted:Rat,Dog,Pig,Cow) 推荐应用：WB,ELISA

  • BN41748R-100ul

    100ul

    ¥2360.00

    交叉反应：Human,Mouse(predicted:Rat,Dog,Pig,Cow) 推荐应用：WB,ELISA

  • BN41748R-200ul

    200ul

    ¥3490.00

    交叉反应：Human,Mouse(predicted:Rat,Dog,Pig,Cow) 推荐应用：WB,ELISA

英文名称EAAT3
中文名称胶质细胞谷氨酸运载蛋白3/神经/上皮细胞谷氨酸运载蛋白抗体
别    名Excitatory amino acid transporters 3; Slc1a1; Eaac1; Eaat3; SLC1A1; EAAC1; EAAT3; solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1; EAAC 2; Excitatory amino acid carrier 1; Excitatory amino acid carrier 2; Excitatory amino acid carrier1; MEAAC 1; MEAAC1; Neuronal and epithelial glutamate transporter; REAAC 1; REAAC1; Slc1 a1; Slc1a 1; Slc1a1; Sodium dependent glutamate/aspartate transporter 3; Solute carrier family 1, member 1; EAA3_HUMAN.  




研究领域免疫学  神经生物学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=1ug/Test 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量58kDa
细胞定位细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human EAAT3:451-524/524 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect.

Function:
Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively regulated by ARL6IP5 (By similarity).

Subunit:
Interacts with ARL6IP5/PRAF3.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in all tissues tested including liver, muscle, testis, ovary, retinoblastoma cell line, neurons and brain (in which there was dense expression in substantia nigra, red nucleus, hippocampus and in cerebral cortical layers).

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A1 subfamily.

SWISS:
P43005

Gene ID:
6505

Database links:

Entrez Gene: 6505 Human

Entrez Gene: 20510 Mouse

Entrez Gene: 25550 Rat

Omim: 133550 Human

SwissProt: P43005 Human

SwissProt: P51906 Mouse

SwissProt: P51907 Rat

Unigene: 444915 Human

Unigene: 246670 Mouse

Unigene: 6384 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

胶质细胞谷氨酸运载蛋白3又称：神经/上皮细胞谷氨酸运载蛋白

















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