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组蛋白H1抗体
  • 产品货号：
    BN41709R
  • 中文名称：
    组蛋白H1抗体
  • 英文名称：
    Rabbit anti-Histone H1t Polyclonal antibody

  • 货号

    产品规格

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  • BN41709R-50ul

    50ul

    ¥1486.00

    交叉反应：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Rabbit) 推荐应用：WB,ELISA

  • BN41709R-100ul

    100ul

    ¥2360.00

    交叉反应：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Rabbit) 推荐应用：WB,ELISA

  • BN41709R-200ul

    200ul

    ¥3490.00

    交叉反应：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Rabbit) 推荐应用：WB,ELISA

英文名称Histone H1t
中文名称组蛋白H1抗体
别    名H1 histone family, member T (testis specific); H1FT; H1T; H1T_HUMAN; Hist1h1t; Histone cluster 1, H1t; Testicular H1 histone.  


研究领域肿瘤  免疫学  转录调节因子  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量22kDa
细胞定位细胞核 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Testicular H1 histone:51-207/207 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Function:
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.

Subcellular Location:
Nucleus. Chromosome.

Post-translational modifications:
Phosphorylated in early spermatids.

Similarity:
Belongs to the histone H1/H5 family.
Contains 1 H15 (linker histone H1/H5 globular) domain.

SWISS:
P22492

Gene ID:
3010

Database links:

Entrez Gene: 3010 Human

Omim: 142712 Human

SwissProt: P22492 Human

Unigene: 533293 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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