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转录同源蛋白质CUX2抗体
  • 产品货号:
    BN41668R
  • 中文名称:
    转录同源蛋白质CUX2抗体
  • 英文名称:
    Rabbit anti-Cux2 Polyclonal antibody
  • 货号

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  • BN41668R-50ul

    50ul

    ¥1486.00

    交叉反应:Rat,Human(predicted:Sheep,Cow,Pig,Dog,Mouse) 推荐应用:IHC-P,IHC-F,IF,ELISA

  • BN41668R-100ul

    100ul

    ¥2360.00

    交叉反应:Rat,Human(predicted:Sheep,Cow,Pig,Dog,Mouse) 推荐应用:IHC-P,IHC-F,IF,ELISA

  • BN41668R-200ul

    200ul

    ¥3490.00

    交叉反应:Rat,Human(predicted:Sheep,Cow,Pig,Dog,Mouse) 推荐应用:IHC-P,IHC-F,IF,ELISA

英文名称Cux2
中文名称转录同源蛋白质CUX2抗体
别    名CDP2; Cut like homeobox 2; Cut-like 2; CUTL2; CUX2; Homeobox protein cut-like 2; Homeobox protein cux 2; Homeobox protein Cux-2; KIAA0293; CUX2_HUMAN.  
研究领域神经生物学  信号转导  干细胞  转录调节因子  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Rat,  (predicted: Mouse, Dog, Pig, Cow, Sheep, )
产品应用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量162kDa
细胞定位细胞核 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Cux2:1001-1085/1486 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Cux2 is a marker for cortical subpopulations. Cux2 is an orthologue of the Drosophila cut gene, which encodes a homeodomain protein involved in neuronal specification. During cortical development Cux2 identifies two subpopulations with different spatial origins, migratory behaviours and phenotypic characteristics: (i) a population of interneurons, which invades the pallium from the subpallium; and (ii) a neuronal population produced in the pallium around embryonic day 11.5, which divides in the SVZ and accumulates in the intermediate zone (IZ). Subsequently, Cux2 is a marker of upper cortical layers.

Function:
May be a transcription factor involved in neural specification. Binds to DNA in a sequence-specific manner

Subcellular Location:
Nuclear

Similarity:
Belongs to the CUT homeobox family.
Contains 3 CUT DNA-binding domains.
Contains 1 homeobox DNA-binding domain.

SWISS:
O14529

Gene ID:
23316

Database links:

Entrez Gene: 23316 Human

Entrez Gene: 13048 Mouse

Entrez Gene: 288665 Rat

Omim: 610648 Human

SwissProt: O14529 Human

SwissProt: P70298 Mouse

Unigene: 124953 Human

Unigene: 156172 Mouse

Unigene: 332661 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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