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BN41648R-50ul
50ul
¥1486.00
交叉反应：Human,Mouse,Rat 推荐应用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
BN41648R-100ul
100ul
¥2360.00
交叉反应：Human,Mouse,Rat 推荐应用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
BN41648R-200ul
200ul
¥3490.00
交叉反应：Human,Mouse,Rat 推荐应用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
| 英文名称 | Egr1 |
| 中文名称 | 早期生长应答蛋白1抗体 |
| 别 名 | Egr-1; Early growth response 1; Krox-24; Ngf1; Ngfi; NGFI-A; zif-268; Egr1; A530045N19Rik; egr; Egr-1; ETR103; Krox-1; Krox-24; Krox24; NGF1-A; NGFI-A; NGFIA; TIS8; Zenk; Zfp-6; AT 225; AT225; Early growth response protein 1; G0S 30; G0S30; KROX 24; Krox 24 protein; KROX24; TIS 8; TIS8; Transcription factor ETR 103; Transcription factor ETR103; Transcription factor Zif 268; Transcription factor Zif268; Zfp 6; ZIF268; Zinc finger protein 225; ZNF 225; ZNF225; EGR1_HUMAN. |
| 研究领域 | 细胞生物 免疫学 信号转导 生长因子和激素 细胞周期蛋白 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2ug/test IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 60kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Egr-1:401-500/453 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. [provided by RefSeq]. Function: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation. Subcellular Location: Nucleus. Similarity: Belongs to the EGR C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers. SWISS: P18146 Gene ID: 1958 Database links: Entrez Gene: 1958 Human Entrez Gene: 13653 Mouse Omim: 128990 Human SwissProt: P18146 Human SwissProt: P08046 Mouse Unigene: 326035 Human Unigene: 708393 Human Unigene: 181959 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Egr-1为即刻早期基因家族中的一个成员,是一种含3个锌指结构的转录因子。有研究表明EGR-1在细胞生长分化中发挥重要作用，如在细胞周期G1-S期的转换过程中Egr-1被诱导表达。 |
