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骨形态发生蛋白2抗体
  • 产品货号:
    BN41646R
  • 中文名称:
    骨形态发生蛋白2抗体
  • 英文名称:
    Rabbit anti-BMP2 Polyclonal antibody
  • 货号

    产品规格

    售价

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  • BN41646R-50ul

    50ul

    ¥1486.00

    交叉反应:Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,GuineaPig) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

  • BN41646R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,GuineaPig) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

  • BN41646R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,GuineaPig) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

英文名称BMP2
中文名称骨形态发生蛋白2抗体
别    名Bone morphogenetic protein 2; BMP 2; BMP 2A; BMP2A; BMP-2; BMP2_HUMAN.  
研究领域细胞生物  免疫学  发育生物学  神经生物学  生长因子和激素  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Guinea Pig, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量13/44kDa
细胞定位分泌型蛋白 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human BMP2:341-396/396 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis.

Function:
Induces cartilage and bone formation.

Subunit:
Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with GREM2, RGMA, RGMB and RGMC. Interacts with ASPN.

Subcellular Location:
Secreted.

Tissue Specificity:
Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.

Similarity:
Belongs to the TGF-beta family.

SWISS:
P12643

Gene ID:
650

Database links:

Entrez Gene: 650 Human

Entrez Gene: 12156 Mouse

Entrez Gene: 29373 Rat

Omim: 112261 Human

SwissProt: P12643 Human

SwissProt: P21274 Mouse

SwissProt: P49001 Rat

Unigene: 73853 Human

Unigene: 103205 Mouse

Unigene: 90931 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.














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