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外周髓磷脂P0蛋白/P0蛋白抗体
  • 产品货号:
    BN41528R
  • 中文名称:
    外周髓磷脂P0蛋白/P0蛋白抗体
  • 英文名称:
    Rabbit anti-Myelin Protein Zero Polyclonal antibody
  • 货号

    产品规格

    售价

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  • BN41528R-50ul

    50ul

    ¥1486.00

    交叉反应:Dog,Rat,Mouse(predicted:GuineaPig,Rabbit,Horse,Cow,Pig,Human) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

  • BN41528R-100ul

    100ul

    ¥2360.00

    交叉反应:Dog,Rat,Mouse(predicted:GuineaPig,Rabbit,Horse,Cow,Pig,Human) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

  • BN41528R-200ul

    200ul

    ¥3490.00

    交叉反应:Dog,Rat,Mouse(predicted:GuineaPig,Rabbit,Horse,Cow,Pig,Human) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

英文名称Myelin Protein Zero
中文名称外周髓磷脂P0蛋白/P0蛋白抗体
别    名peripheral myelin prothein Zero; MPZ; MPP; Myelin P0 protein; CHM; CMT1; CMT1B; DSS; MYELIN GLYCOPROTEIN P-ZERO; MYELIN PROTEIN PERIPHERAL; Myelin protein zero; P0; MYP0_HUMAN.


研究领域神经生物学  信号转导  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat, Dog,  (predicted: Human, Pig, Cow, Horse, Rabbit, Guinea Pig, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量24kDa
细胞定位细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human P0 protein:175-248/248 <Cytoplasmic>
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Myelin protein-zero is the major structural protein of peripheral myelin, accounting for more than 50% of the protein present in the sheath of peripheral nerves. Expression of the gene encoding Myelin protein-zero (MPZ) is restricted to Schwann cells; MPZ is not found in the CNS. An integral membrane glycoprotein of ~28kDa, Myelin protein-zero is thought to link adjacent lamellae and thereby stabilize the myelin assembly. The other 3 major components of myelin are myelin basic protein, myelin proteolipid protein and myelin-associated glycoprotein.

Subunit:
Homodimer and homotetramer.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Tissue Specificity:
Found only in peripheral nervous system Schwann cells.

Similarity:
Belongs to the myelin P0 protein family.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

SWISS:
P25189

Gene ID:
4359

Database links:

Entrez Gene: 4359 Human

Entrez Gene: 17528 Mouse

Omim: 159440 Human

SwissProt: P25189 Human

SwissProt: P27573 Mouse

 Unigene: 591486 Human

Unigene: 93883 Human

Unigene: 9986 Mouse

 UniProtKB/Swiss-Prot: P25189.1




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

成熟的周围神经系统髓鞘主要的蛋白为P0蛋白,分子量28KDa,它具有单个跨膜区,是IgG超家族的成员之一。

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