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WDFY3蛋白抗体
  • 产品货号:
    BN41414R
  • 中文名称:
    WDFY3蛋白抗体
  • 英文名称:
    Rabbit anti-WDFY3 Polyclonal antibody
  • 货号

    产品规格

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  • BN41414R-100ul

    100ul

    ¥2360.00

    交叉反应:Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用:IHC-P,IHC-F,IF,ELISA

  • BN41414R-200ul

    200ul

    ¥3490.00

    交叉反应:Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用:IHC-P,IHC-F,IF,ELISA

英文名称WDFY3
中文名称WDFY3蛋白抗体
别    名Alfy; Autophagy linked FYVE protein; KIAA0993; MGC16461; WD repeat and FYVE domain containing 3; ZFYVE25; WDFY3_HUMAN.  
研究领域心血管  细胞自噬  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量395kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human WDFY3:951-1050/3526 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍WDFY3 was identified in a screen for phosphatidylinositol 3 phosphate binding proteins. The FYVE domain is a zinc binding domain found in many PtdIns binding proteins and is proposed to target proteins to membrane lipids. WDFY3 has been shown localized to the nuclear membrane and within autophagic membranes and it is proposed to function as a link between protein aggregates and the autophagic machinery. WDFY3 is also known as autophagy linked FYVE protein.

Subcellular Location:
Membrane; Peripheral membrane protein; Cytoplasmic side. Note: Colocalizes with autophagic structures in starved cells.

Tissue Specificity:
Ubiquitous.

Similarity:
Contains 1 BEACH domain.
Contains 1 FYVE-type zinc finger.
Contains 5 WD repeats.

SWISS:
Q8IZQ1

Gene ID:
23001

Database links:

Entrez Gene: 23001 Human

SwissProt: Q8IZQ1 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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