首页>>蛋白研究>>抗体>>甘油二酯胆碱磷酸转移酶抗体
甘油二酯胆碱磷酸转移酶抗体
  • 产品货号：
    BN41402R
  • 中文名称：
    甘油二酯胆碱磷酸转移酶抗体
  • 英文名称：
    Rabbit anti-CHPT1 Polyclonal antibody

  • 货号

    产品规格

    售价

    备注

  • BN41402R-100ul

    100ul

    ¥2360.00

    交叉反应：Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用：WB,ELISA

  • BN41402R-200ul

    200ul

    ¥3490.00

    交叉反应：Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用：WB,ELISA

英文名称CHPT1
中文名称甘油二酯胆碱磷酸转移酶抗体
别    名AAPT1-like protein; Cholinephosphotransferase 1; chpt1; CHPT1_HUMAN; Diacylglycerol cholinephosphotransferase 1; hCPT1.  
研究领域肿瘤  心血管  细胞生物  免疫学  细胞周期蛋白  细胞分化  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量45kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human CHPT1:61-160/406 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍CHPT1, also known as AAPT1-like protein and Diacylglycerol cholinephosphotransferase 1, is a 406 amino acid multi-pass membrane protein that is localized to the golgi apparatus. By catalyzing the phosphatidylcholine biosynthesis from CDP-choline, it plays an essential role in the formation and maintenance of vesicular membranes. CHPT1 is most abundant in testis, as well as small intestine, heart, colon, spleen and prostate. Expression of CHPT1 is increased in cancerous breast cells as compared to normal breast cell lines and it has been determined that the CHPT1 gene exhibits mutations within the cancerous cells. Interestingly, exposure to mustard gas significantly decreases CHPT1 gene expression and activity, an event that may play an important role in the development of acute respiratory distress syndrome (ARDS). There are two isoforms of CHPT1 that are produced as a result of alternative splicing events.

Function:
Catalyzes phosphatidylcholine biosynthesis from CDP-choline. It thereby plays a central role in the formation and maintenance of vesicular membranes.

Subcellular Location:
Golgi apparatus membrane.

Tissue Specificity:
Highly expressed in testis, colon, small intestine, heart, prostate and spleen. Also detected in kidney, skeletal muscle, pancreas, leukocytes, ovary and thymus. Weakly expressed in the brain, placenta and lung. Overexpressed in cancerous breast epithelial cell lines.

Similarity:
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

SWISS:
Q8WUD6

Gene ID:
56994

Database links:

Entrez Gene: 56994 Human

SwissProt: Q8WUD6 Human

Unigene: 293077 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
















image.png