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9号染色体开放阅读框86抗体
  • 产品货号:
    BN41393R
  • 中文名称:
    9号染色体开放阅读框86抗体
  • 英文名称:
    Rabbit anti-C9orf86 Polyclonal antibody
  • 货号

    产品规格

    售价

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  • BN41393R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse,Rat 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN41393R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse,Rat 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

英文名称C9orf86
中文名称9号染色体开放阅读框86抗体
别    名Chromosome 9 open reading frame 86; FLJ10101; Hypothetical protein LOC55684; KIAA1984; Parf; Partner of ARF; pp8875; Putative GTP binding protein Parf; Rab like GTP binding protein 1; Rab like GTP binding protein 1C; Rab like protein 1; RBEL1; RP11-216L13.9.  
研究领域肿瘤  细胞生物  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, 
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量80kDa
细胞定位细胞核 细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human C9orf86:631-729/729 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍C9orf86 (Partner of ARF;PARF) binds p19(ARF), but not the p16(INK4A) isoform of CDKN2A. Knockdown of C9orf86 by RNA interference reduced the growth inhibitory activity of p19(ARF) and enhanced the rate of cell proliferation.

Function:
May enhance cellular proliferation. May reduce growth inhibitory activity of CDKN2A.

Subcellular Location:
Cytoplasmic and Nuclear. Note=Predominantly cytoplasmic. Proposed to shuttle between cytoplasm and nucleus.

Post-translational modifications:
Isoform 1 is O-glycosylated, while other isoforms are not.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

SWISS:
Q3YEC7

Gene ID:
55684

Database links:

Entrez Gene: 55684 Human

Entrez Gene: 227624 Mouse

Entrez Gene: 227624 Rat

Omim: 610615 Human

SwissProt: Q3YEC7 Human

SwissProt: Q5U3K5 Mouse

Unigene: 370555 Human

Unigene: 29600 Mouse

Unigene: 443064 Mouse

Unigene: 17709 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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