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AKIRIN2蛋白抗体
  • 产品货号:
    BN41362R
  • 中文名称:
    AKIRIN2蛋白抗体
  • 英文名称:
    Rabbit anti-AKIRIN2 Polyclonal antibody
  • 货号

    产品规格

    售价

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  • BN41362R-100ul

    100ul

    ¥2360.00

    交叉反应:Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep) 推荐应用:IHC-P,IHC-F,IF,ELISA

  • BN41362R-200ul

    200ul

    ¥3490.00

    交叉反应:Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep) 推荐应用:IHC-P,IHC-F,IF,ELISA

英文名称AKIRIN2
中文名称AKIRIN2蛋白抗体
别    名AKIR2_HUMAN; AKIRIN 2; Akirin-2; Akirin2; C6orf166; dJ486L4.2; FBI1; FLJ10342; Fourteen three three beta interactant 1.  
研究领域细胞生物  免疫学  染色质和核信号  信号转导  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, )
产品应用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量22kDa
细胞定位细胞核 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human AKIRIN2:51-150/203 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1.

Function:
Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity).

Subunit:
Interacts with YWHAB (By similarity).

Subcellular Location:
Nucleus

Tissue Specificity:
Widely expressed with the highest expression in peripheral blood leukocytes

Similarity:
Belongs to the akirin family.

SWISS:
Q53H80

Gene ID:
55122

Database links:

Entrez Gene: 55122 Human

Entrez Gene: 433693 Mouse

Entrez Gene: 297968 Rat

Omim: 615165 Human

SwissProt: Q53H80 Human

SwissProt: B1AXD8 Mouse

SwissProt: Q25C79 Rat

Unigene: 485915 Human

Unigene: 389532 Mouse

Unigene: 399624 Mouse

Unigene: 3858 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.











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