货号
产品规格
售价
备注
BN41362R-100ul
100ul
¥2360.00
交叉反应:Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep) 推荐应用:IHC-P,IHC-F,IF,ELISA
BN41362R-200ul
200ul
¥3490.00
交叉反应:Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep) 推荐应用:IHC-P,IHC-F,IF,ELISA
英文名称 | AKIRIN2 |
中文名称 | AKIRIN2蛋白抗体 |
别 名 | AKIR2_HUMAN; AKIRIN 2; Akirin-2; Akirin2; C6orf166; dJ486L4.2; FBI1; FLJ10342; Fourteen three three beta interactant 1. |
研究领域 | 细胞生物 免疫学 染色质和核信号 信号转导 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Mouse, (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, ) |
产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 22kDa |
细胞定位 | 细胞核 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human AKIRIN2:51-150/203 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
产品介绍 | Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1. Function: Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity). Subunit: Interacts with YWHAB (By similarity). Subcellular Location: Nucleus Tissue Specificity: Widely expressed with the highest expression in peripheral blood leukocytes Similarity: Belongs to the akirin family. SWISS: Q53H80 Gene ID: 55122 Database links: Entrez Gene: 55122 Human Entrez Gene: 433693 Mouse Omim: 615165 Human SwissProt: Q53H80 Human SwissProt: B1AXD8 Mouse Unigene: 485915 Human Unigene: 389532 Mouse Unigene: 399624 Mouse Unigene: 3858 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |