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生长抑素抗体
  • 产品货号：
    BN41355R
  • 中文名称：
    生长抑素抗体
  • 英文名称：
    Rabbit anti-Somatostatin 28 Polyclonal antibody

  • 货号

    产品规格

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  • BN41355R-100ul

    100ul

    ¥2360.00

    交叉反应：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Rabbit) 推荐应用：IHC-P,IHC-F,ICC,IF,ELISA

  • BN41355R-200ul

    200ul

    ¥3490.00

    交叉反应：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Rabbit) 推荐应用：IHC-P,IHC-F,ICC,IF,ELISA

英文名称Somatostatin 28
中文名称生长抑素抗体
别    名Growth hormone release inhibiting factor; SMS_HUMAN; SMST; SST; Somatostatin 28; Somatostatin28; Somatostatin-28; Somatostatin-28; somatostatin SS28.  
研究领域细胞生物  发育生物学  神经生物学  干细胞  生长因子和激素  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, )
产品应用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:200-800 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量3kDa
细胞定位分泌型蛋白 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Somatostatin 28:51-116/116 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Somatostatin is a regulatory hormone that is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G protein-coupled somatostatin receptors. This cyclic tetradecapeptide inhibits the secretion of many important hormones, including somatotropin (also designated growth hormone, or GH), insulin and glucagon. Somatostatin is found in both the hypothalamus and pancreas. Somatostatin is thought to be involved in the regulation of insulin synthesis. The hormone somatostatin has active 14 amino acid and 28 amino acid forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. In the cerebellum, Somatostatin-14 and Somatostatin-28 are highly expressed at birth and in the adult stage, respectively. Somatostatin affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. The gene encoding Somatostatin maps to human chromosome 3q28.

Function:
The cyclic tetradecapeptide somatostatin is widely distributed throughout the body and is an important regulator of endocrine and nervous system function. It exerts its biologic actions by binding to specific high affinity receptors on the cell surface. Somatostatin inhibits the release of somatotropin. Somatostatin has also been shown in sympathetic nerves, mucosal cells, myenteric nerves of the gastrointestinal tract, salivary glands and in some parafollicular cells of the thyroid. Somatostatin positive cells may also be present in medullary thyroid carcinomas, C cell hyperplasia, thymic and lung tumors and pulmonary small cell carcinomas.

Subcellular Location:
Secreted.

Similarity:
Belongs to the somatostatin family.

SWISS:
P61278

Gene ID:
6750

Database links:

Entrez Gene: 396279 Chicken

Entrez Gene: 280932 Cow

Entrez Gene: 6750 Human

Entrez Gene: 20604 Mouse

Entrez Gene: 24797 Rat

Omim: 182450 Human

SwissProt: P33094 Chicken

SwissProt: P26917 Cow

SwissProt: P61278 Human

SwissProt: P60041 Mouse

SwissProt: P60042 Rat

Unigene: 12409 Human

Unigene: 34418 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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