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CXC趋化因子16抗体
  • 产品货号：
    BN41354R
  • 中文名称：
    CXC趋化因子16抗体
  • 英文名称：
    Rabbit anti-CXCL16 Polyclonal antibody

  • 货号

    产品规格

    售价

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  • BN41354R-100ul

    100ul

    ¥2360.00

    交叉反应：Human 推荐应用：WB,IHC-F,ICC,IF,ELISA

  • BN41354R-200ul

    200ul

    ¥3490.00

    交叉反应：Human 推荐应用：WB,IHC-F,ICC,IF,ELISA

英文名称CXCL16
中文名称CXC趋化因子16抗体
别    名CXC-chemokine ligand 16; Chemokine (C X C motif) ligand 16; CXC chemokine ligand 16; CXCLG16; Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SCYB16; Small inducible cytokine B16 precursor; SRPSOX; Transmembrane chemokine CXCL16; CXL16_HUMAN.  
研究领域肿瘤  细胞生物  免疫学  信号转导  细胞表面分子  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, 
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量24kDa
细胞定位细胞膜 分泌型蛋白 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human CXCL16:41-140/254 <Extracellular>
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍CXCL16 acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis. It induces a strong chemotactic response and calcium mobilization. It binds to CXCR6/Bonzo.

Function:
Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.

Subcellular Location:
Cell membrane. Secreted. Also exists as a soluble form.

Tissue Specificity:
Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the intercrine alpha (chemokine CxC) family.

SWISS:
Q9H2A7

Gene ID:
58191

Database links:

Entrez Gene: 58191 Human

Omim: 605398 Human

SwissProt: Q9H2A7 Human

Unigene: 513885 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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