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核通道蛋白SEH1L抗体
  • 产品货号：
    BN41350R
  • 中文名称：
    核通道蛋白SEH1L抗体
  • 英文名称：
    Rabbit anti-SEH1L Polyclonal antibody

  • 货号

    产品规格

    售价

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  • BN41350R-100ul

    100ul

    ¥2360.00

    交叉反应：Rat(predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Rabbit) 推荐应用：IHC-P,IHC-F,ICC,IF,ELISA

  • BN41350R-200ul

    200ul

    ¥3490.00

    交叉反应：Rat(predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Rabbit) 推荐应用：IHC-P,IHC-F,ICC,IF,ELISA

英文名称SEH1L
中文名称核通道蛋白SEH1L抗体
别    名Nucleoporin SEH1; Nup107-160 subcomplex subunit SEH1; SEC13-like protein; SEC13L; Seh 1; SEH1-like (S. cerevisiae); SEH1_HUMAN; SEH1A; SEH1B; SEH1L  
研究领域细胞生物  免疫学  染色质和核信号  信号转导  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Rat,  (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Rabbit, )
产品应用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量40kDa
细胞定位细胞核 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human SEH1L:1-100/360 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Seh1 is a 421 amino acid protein belonging to the WD repeat Sec13 family. Localized to the nucleus, Seh1 is a component of the nuclear pore complex Nup107-160. Nuclear pore complexes control bidirectional transport of macromolecules between the cytoplasm and the nucleus. All components of the complex Nup107-160, including Seh1, localize to the kinetochores during mitosis. Seh1 is expressed as two isoforms produced by alternative splicing and contains six WD repeats.

Function:
Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.

Subcellular Location:
Chromosome; centromere; kinetochore. Nucleus; nuclear pore complex.

Similarity:
Belongs to the WD repeat SEC13 family.
Contains 6 WD repeats.

SWISS:
Q96EE3

Gene ID:
81929

Database links:

Entrez Gene: 81929 Human

Omim: 609263 Human

SwissProt: Q96EE3 Human

Unigene: 301048 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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