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双重特异性磷酸酶27抗体
  • 产品货号：
    BN41349R
  • 中文名称：
    双重特异性磷酸酶27抗体
  • 英文名称：
    Rabbit anti-DUSP27 Polyclonal antibody

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    产品规格

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  • BN41349R-100ul

    100ul

    ¥2360.00

    交叉反应：Human(predicted:Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用：WB

  • BN41349R-200ul

    200ul

    ¥3490.00

    交叉反应：Human(predicted:Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用：WB

英文名称DUSP27
中文名称双重特异性磷酸酶27抗体
别    名Atypical dual specific protein phosphatase; Dual specificity phosphatase 27; Dual specificity phosphatase and pro isomerase domain containing 1; Dual specificity phosphatase DUPD1; dupd1; DUPD1_HUMAN; DUSP27; OTTHUMP00000019871.  
研究领域细胞生物  信号转导  激酶和磷酸酶  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,  (predicted: Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量25kDa
细胞定位细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human DUSP27:21-120/220 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members, including MAPK/ERK, SAPK/JNK and p38. DUSP27 (dual specificity phosphatase 27), also known as FMDSP or DUPD1 (dual specificity phosphatase and pro isomerase domain containing 1), is a 220 amino acid cytoplasmic protein that belongs to the protein-tyrosine phosphatase family. Expressed in skeletal muscle, liver and adipose tissue, DUSP27 may play a role in energy metabolism. The gene encoding DUSP27 is referred to as DUPD1 and maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.

Subunit:
Homodimer.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Skeletal muscle, liver and adipose tissue.

Similarity:
elongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 tyrosine-protein phosphatase domain.

SWISS:
Q68J44

Gene ID:
338599

Database links:

Entrez Gene: 338599 Human

SwissProt: Q68J44 Human

Unigene: 535090 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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