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GTP酶IMAP家族成员1抗体
  • 产品货号：
    BN41312R
  • 中文名称：
    GTP酶IMAP家族成员1抗体
  • 英文名称：
    Rabbit anti-GIMAP1 Polyclonal antibody

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    产品规格

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  • BN41312R-100ul

    100ul

    ¥2360.00

    交叉反应：Rat(predicted:Human,Mouse,Horse,Rabbit) 推荐应用：IHC-P,IHC-F,IF

  • BN41312R-200ul

    200ul

    ¥3490.00

    交叉反应：Rat(predicted:Human,Mouse,Horse,Rabbit) 推荐应用：IHC-P,IHC-F,IF

英文名称GIMAP1
中文名称GTP酶IMAP家族成员1抗体
别    名GIMA1_HUMAN; GIMAP1; GTPase IMAP family member 1; hIMAP1; Immunity-associated protein 1.  
研究领域细胞生物  免疫学  G蛋白偶联受体  G蛋白信号  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Rat,  (predicted: Human, Mouse, Horse, Rabbit, )
产品应用IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量34kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human GIMAP1:31-130/306 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The GTPase of the immunity-associated protein (GIMAP) family of proteins include seven members that are expressed by genes residing on human chromosome 7. GIMAP proteins have been implicated in the regulation of lymphomyeloid cell survival. GIMAP1 (GTPase, IMAP family member 1), also known as IMAP1 (immunity-associated protein 1), HIMAP1 or IMAP38, is a 306 amino acid single-pass type IV membrane protein of the endoplasmic reticulum (ER) belonging to the GIMAP family. Encoded by a gene located on human chromosome 7, GIMAP1 is expressed primarily in spleen with lower levels found in lymph node. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Function:
May regulate lymphocyte survival. Required for normal levels of mature T-lymphocytes and mature B-cells (By similarity).

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Golgi apparatus membrane (By similarity).

Tissue Specificity:
Predominantly expressed in the spleen and to a lesser extent in the lymph nodes.

Similarity:
Belongs to the IAN GTP-binding protein family.

SWISS:
Q8WWP7

Gene ID:
170575

Database links:

Entrez Gene: 170575 Human

Omim: 608084 Human

SwissProt: Q8WWP7 Human

Unigene: 647087 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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