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法尼基二磷酸合酶1抗体
  • 产品货号:
    BN41298R
  • 中文名称:
    法尼基二磷酸合酶1抗体
  • 英文名称:
    Rabbit anti-GGPS1 Polyclonal antibody
  • 货号

    产品规格

    售价

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  • BN41298R-100ul

    100ul

    ¥2360.00

    交叉反应:Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit) 推荐应用:WB,ELISA

  • BN41298R-200ul

    200ul

    ¥3490.00

    交叉反应:Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit) 推荐应用:WB,ELISA

英文名称GGPS1
中文名称法尼基二磷酸合酶1抗体
别    名(2E antibody 6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate synthase 1; Geranylgeranyl diphosphate synthase; Geranylgeranyl pyrophosphate synthase; Geranylgeranyl pyrophosphate synthetase; Geranyltranstransferase; GGPP synthase; GGPP synthetase; GGPPS; GGPPS_HUMAN; GGPPS1; GGPPSase; GGPS1.  
研究领域肿瘤  细胞生物  信号转导  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
产品应用WB=1:500-1000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量35kDa
细胞定位细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human GGPS1:30-100/300 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene. [provided by RefSeq, Sep 2010].

Function:
Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.

Subunit:
Homohexamer; trimer of homodimers

Subcellular Location:
Cytoplasm.

Similarity:
Abundantly expressed in testis. Found in other tissues to a lower extent.
Belongs to the FPP/GGPP synthase family.

SWISS:
O95749

Gene ID:
9453

Database links:

Entrez Gene: 9453 Human

Entrez Gene: 14593 Mouse

Entrez Gene: 291211 Rat

Omim: 606982 Human

SwissProt: O95749 Human

SwissProt: Q9WTN0 Mouse

SwissProt: Q6F596 Rat

Unigene: 647791 Human

Unigene: 148039 Mouse

Unigene: 54975 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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