首页>>蛋白研究>>抗体>>细胞周期蛋白G相关激酶抗体
细胞周期蛋白G相关激酶抗体
  • 产品货号：
    BN41287R
  • 中文名称：
    细胞周期蛋白G相关激酶抗体
  • 英文名称：
    Rabbit anti-GAK protein Polyclonal antibody

  • 货号

    产品规格

    售价

    备注

  • BN41287R-100ul

    100ul

    ¥2360.00

    交叉反应：Mouse(predicted:Human,Rat,Chicken,Dog,Cow,Horse) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA

  • BN41287R-200ul

    200ul

    ¥3490.00

    交叉反应：Mouse(predicted:Human,Rat,Chicken,Dog,Cow,Horse) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA

英文名称GAK protein
中文名称细胞周期蛋白G相关激酶抗体
别    名Cyclin G associated kinase; Cyclin-G-associated kinase; EC 2.7.11.1; FLJ16629; FLJ40395; GAK; GAK protein; GAK_HUMAN; MGC99654.  
研究领域细胞生物  神经生物学  信号转导  细胞周期蛋白  激酶和磷酸酶  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse,  (predicted: Human, Rat, Chicken, Dog, Cow, Horse, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量144kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human GAK protein:244-330/1311 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.
Tissue specificity: Ubiquitous. Highest in testis.

Function:
Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.

Subcellular Location:
Cytoplasm, perinuclear region. Golgi apparatus, trans-Golgi network. Cell junction, focal adhesion (Probable). Note=Localizes to the perinuclear area and to the trans-Golgi network. Also seen on the plasma membrane, probably at focals adhesions.

Tissue Specificity:
Ubiquitous. Highest in testis.

Similarity:
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Contains 1 C2 tensin-type domain.
Contains 1 J domain.
Contains 1 phosphatase tensin-type domain.
Contains 1 protein kinase domain.

SWISS:
O14976

Gene ID:
2580

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












image.png