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脉周蛋白1抗体(胃癌抗原蛋白Ga50)
  • 产品货号:
    BN41281R
  • 中文名称:
    脉周蛋白1抗体(胃癌抗原蛋白Ga50)
  • 英文名称:
    Rabbit anti-PPHLN1 Polyclonal antibody
  • 货号

    产品规格

    售价

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  • BN41281R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit) 推荐应用:WB,IHC-P,ELISA

  • BN41281R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit) 推荐应用:WB,IHC-P,ELISA

英文名称PPHLN1
中文名称脉周蛋白1抗体(胃癌抗原蛋白Ga50)
别    名Gastric cancer antigen Ga50; Periphilin 1; Periphilin-1; PPHLN_HUMAN; PPHLN1.  
研究领域细胞生物  免疫学  细胞周期蛋白  细胞分化  细胞类型标志物  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Rabbit, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量53kDa
细胞定位细胞核 细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human PPHLN1:301-400/458 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Involved in epithelial differentiation and contributes to epidermal integrity and barrier formation.

Function:
Involved in epithelial differentiation and contributes to epidermal integrity and barrier formation.

Subunit:
Homodimer. Interacts with PPL.

Subcellular Location:
Nucleus. Cytoplasm.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Substrate of transglutaminase (in vitro).

SWISS:
Q8NEY8

Gene ID:
51535

Database links:
 UniProtKB/Swiss-Prot: Q8NEY8.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

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