首页>>蛋白研究>>抗体>>还原型辅酶Ⅱ氧化酶5/烟酰胺腺嘌呤二核苷酸磷酸抗体
还原型辅酶Ⅱ氧化酶5/烟酰胺腺嘌呤二核苷酸磷酸抗体
  • 产品货号：
    BN41234R
  • 中文名称：
    还原型辅酶Ⅱ氧化酶5/烟酰胺腺嘌呤二核苷酸磷酸抗体
  • 英文名称：
    Rabbit anti-NOX5 Polyclonal antibody

  • 货号

    产品规格

    售价

    备注

  • BN41234R-100ul

    100ul

    ¥2360.00

    交叉反应：Mouse(predicted:Human,Dog,Pig,Cow,Horse,Rabbit) 推荐应用：WB,ELISA

  • BN41234R-200ul

    200ul

    ¥3490.00

    交叉反应：Mouse(predicted:Human,Dog,Pig,Cow,Horse,Rabbit) 推荐应用：WB,ELISA

英文名称NOX5
中文名称还原型辅酶Ⅱ氧化酶5/烟酰胺腺嘌呤二核苷酸磷酸抗体
别    名NADPH oxidase 5; NADPH oxidase EFhand calcium binding domain 5; NOX5; NOX5_HUMAN; MGC149776; MGC149777.  
研究领域细胞生物  信号转导  细胞凋亡  细胞周期蛋白  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量84kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human NOX5:675-765/765 <Extracellular>
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis.

Function:
Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis. Isoform v2 and isoform v5 are involved in endothelial generation of reactive oxygen species (ROS), proliferation and angiogenesis and contribute to endothelial response to thrombin.

Subcellular Location:
Membrane; Multi-pass membrane protein (Potential). Isoform v2: Endoplasmic reticulum. Isoform v5: Endoplasmic reticulum.

Tissue Specificity:
Mainly expressed in pachytene spermatocytes of testis and in lymphocyte-rich areas of spleen and lymph nodes. Isoform v1 is expressed in spleen. Isoform v2 is expressed in testis. Also detected in ovary, placenta, pancreas, cardiac fibroblasts. Expressed in B-cells and prostate malignant cells. Isoform v1 and isoform v3 are expressed in epithelial colorectal adenocarcinoma cells. Isoform v2 and isoform v4 are expressed in endothelial cells. Isoform v1, isoform v2, isoform v3 and isoform v4 are expressed in pulmonary artery smooth muscle cells. Isoform v2 and isoform v5 are expressed in microvascular endothelial cells (at protein level).

Similarity:
Contains 4 EF-hand domains.
Contains 1 FAD-binding FR-type domain.
Contains 1 ferric oxidoreductase domain.

SWISS:
Q96PH1

Gene ID:
79400

Database links:

Entrez Gene: 79400 Human

Omim: 606572 Human

SwissProt: Q96PH1 Human

Unigene: 657932 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.















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