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BN41226R-100ul
100ul
¥2360.00
交叉反应：Human,Mouse(predicted:Rat,Pig,Cow) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41226R-200ul
200ul
¥3490.00
交叉反应：Human,Mouse(predicted:Rat,Pig,Cow) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
| 英文名称 | ICAM5 |
| 中文名称 | 细胞间粘附分子5抗体 |
| 别 名 | ICAM5_HUMAN; ICAM5 precursor; Intercellular adhesion molecule 5; Intercellular adhesion molecule 5 precursor; Intercellular adhesion molecule 5, telencephalin; Telencephalin; TLCN; TLN. |
| 研究领域 | 细胞生物 免疫学 神经生物学 细胞粘附分子 细胞类型标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, (predicted: Rat, Pig, Cow, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2ug/test IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 97kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ICAM5:501-600/924 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. Function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon. Similarity: Belongs to the immunoglobulin superfamily. ICAM family. Contains 9 Ig-like C2-type (immunoglobulin-like) domains. SWISS: Q9UMF0 Gene ID: 7087 Database links: Entrez Gene: 7087 Human Entrez Gene: 15898 Mouse Omim: 601852 Human SwissProt: Q9UMF0 Human SwissProt: Q60625 Mouse Unigene: 465862 Human Unigene: 59765 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
