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嗜铬颗粒胺转运蛋白VMAT1抗体
  • 产品货号：
    BN41225R
  • 中文名称：
    嗜铬颗粒胺转运蛋白VMAT1抗体
  • 英文名称：
    Rabbit anti-VMAT1 Polyclonal antibody

  • 货号

    产品规格

    售价

    备注

  • BN41225R-100ul

    100ul

    ¥2360.00

    交叉反应：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse) 推荐应用：WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN41225R-200ul

    200ul

    ¥3490.00

    交叉反应：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse) 推荐应用：WB,IHC-P,IHC-F,ICC,IF,ELISA

英文名称VMAT1
中文名称嗜铬颗粒胺转运蛋白VMAT1抗体
别    名Adrenal chromaffin granule amine transporter; CGAT; CGAT; Chromaffin granule amine transporter; SLC18A1; Solute carrier family 18 (vesicular monoamine), member 1; Solute carrier family 18 member 1; VAT 1; VAT1; Vesicular amine transporter 1; VMAT 1; VMAT1_HUMAN.  
研究领域神经生物学  信号转导  转运蛋白  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量58kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human VMAT1:421-525/525 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008].

Function:
Involved in the vesicular transport of biogenic amines.

Subcellular Location:
Cytoplasmic vesicle membrane; Multi-pass membrane protein.

Similarity:
Belongs to the major facilitator superfamily. Vesicular transporter family.

SWISS:
Q99536

Gene ID:
10493

Database links:

Entrez Gene: 10493 Human

Entrez Gene: 26949 Mouse

Omim: 604631 Human

SwissProt: Q99536 Human

SwissProt: Q62465 Mouse

Unigene: 514199 Human

Unigene: 29210 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.










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