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BN41213R-100ul
100ul
¥2360.00
交叉反应：Human,Mouse(predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Sheep) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
BN41213R-200ul
200ul
¥3490.00
交叉反应：Human,Mouse(predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Sheep) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
| 英文名称 | MDM2BP |
| 中文名称 | 双微体2癌基因结合蛋白抗体 |
| 别 名 | MDM 2 binding protein; MDM 2 BP; MDM2 (mouse double minute 2) binding protein 104kD; MDM2 (mouse double minute 2) binding protein; MDM2 binding protein; MDM2 BP; Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104kDa; Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein; Mdm2 transformed 3T3 cell double minute 2 p53 binding protein binding protein; MDM2BP; Mouse double minute 2 homolog binding protein; MTBP_HUMAN. |
| 研究领域 | 肿瘤 细胞生物 染色质和核信号 细胞周期蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 102kDa |
| 细胞定位 | 细胞核 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MTBP/MDM2BP:821-904/904 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation. Function: Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation. Subunit: Interacts with MDM2. Similarity: Belongs to the MTBP family. SWISS: Q96DY7 Gene ID: 27085 Database links: Entrez Gene: 27085 Human Entrez Gene: 105837 Mouse Omim: 605927 Human SwissProt: Q96DY7 Human SwissProt: Q80VU3 Mouse SwissProt: Q8BJS8 Mouse SwissProt: Q8BTU9 Mouse SwissProt: Q8BTW0 Mouse SwissProt: Q9ER61 Mouse Unigene: 186433 Human Unigene: 46701 Human Unigene: 61901 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
