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BN41200R-100ul
100ul
¥2360.00
交叉反应：Mouse,Rat(predicted:Human,Dog,Cow,Horse,Sheep) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
BN41200R-200ul
200ul
¥3490.00
交叉反应：Mouse,Rat(predicted:Human,Dog,Cow,Horse,Sheep) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
| 英文名称 | ROR beta |
| 中文名称 | 维甲酸相关孤儿受体β抗体 |
| 别 名 | bA133M9.1; NR1F2; Nuclear receptor ROR-beta; Nuclear receptor RZR beta; Nuclear receptor RZR-beta; Nuclear receptor subfamily 1 group F member 2; OTTHUMP00000021486; RAR related orphan receptor B; RAR related orphan receptor beta; Retinoic acid binding receptor beta; Retinoid-related orphan receptor-beta; ROR BETA; Rorb; RORB_HUMAN; RZR BETA; RZRB. |
| 研究领域 | 肿瘤 细胞生物 染色质和核信号 神经生物学 信号转导 细胞周期蛋白 细胞分化 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, Rat, (predicted: Human, Dog, Cow, Horse, Sheep, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 53kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RORB:385-470/470 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | ROR beta is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation. Function: Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter (By similarity). Subcellular Location: Nucleus (Probable). Similarity: Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. SWISS: Q92753 Gene ID: 6096 Database links: Entrez Gene: 6096 Human Entrez Gene: 225998 Mouse Omim: 601972 Human SwissProt: Q92753 Human SwissProt: Q8R1B8 Mouse Unigene: 494178 Human Unigene: 234641 Mouse Unigene: 210157 Rat Unigene: 231652 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
