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跨膜蛋白TMED4抗体
  • 产品货号:
    BN41199R
  • 中文名称:
    跨膜蛋白TMED4抗体
  • 英文名称:
    Rabbit anti-TMED4 Polyclonal antibody
  • 货号

    产品规格

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  • BN41199R-100ul

    100ul

    ¥2360.00

    交叉反应:Mouse,Rat(predicted:Human,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

  • BN41199R-200ul

    200ul

    ¥3490.00

    交叉反应:Mouse,Rat(predicted:Human,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

英文名称TMED4
中文名称跨膜蛋白TMED4抗体
别    名HNLF; Transmembrane emp24 domain containing protein 4; TMED4_HUMAN.  
研究领域肿瘤  染色质和核信号  信号转导  转录调节因子  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,  (predicted: Human, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量23kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human TMED4:41-140/227 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍TMED4 is a putative NF-kB activating protein belonging to the EMP24/GP25L family, and contains 1 GOLD domain. It is also known as Transmembrane emp24 protein transport domain containing 4.

Function:
Involved in vesicular protein trafficking, mainly in the early secretory pathway. targeting. Involved in the maintenance of the Golgi apparatus. Appears to play a role in the biosynthesis of secreted cargo including processing. Involved in endoplasmic reticulum stress response. May play a role in the regulation of heat-shock response and apoptosis

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type I membrane protein

Similarity:
Belongs to the EMP24/GP25L family.
Contains 1 GOLD domain.

SWISS:
Q7Z7H5

Gene ID:
222068

Database links:

Entrez Gene: 222068 Human

Entrez Gene: 103694 Mouse

Entrez Gene: 305502 Rat

Omim: 612038 Human

SwissProt: Q7Z7H5 Human

SwissProt: Q8R1V4 Mouse

Unigene: 598832 Human

Unigene: 715273 Human

Unigene: 254495 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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