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锌指蛋白379抗体
  • 产品货号：
    BN41198R
  • 中文名称：
    锌指蛋白379抗体
  • 英文名称：
    Rabbit anti-ZNF379 Polyclonal antibody

  • 货号

    产品规格

    售价

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  • BN41198R-100ul

    100ul

    ¥2360.00

    交叉反应：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit) 推荐应用：WB

  • BN41198R-200ul

    200ul

    ¥3490.00

    交叉反应：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit) 推荐应用：WB

英文名称ZNF379
中文名称锌指蛋白379抗体
别    名CXorf11; DHHC9; Palmitoyltransferase ZDHHC9; ZDHHC 9; ZDHHC10; Zinc finger DHHC domain containing protein 9; Zinc finger protein 379; ZNF379; ZNF380; ZDHC9_HUMAN.  
研究领域肿瘤  信号转导  肿瘤细胞生物标志物  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
产品应用WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量40kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ZNF379/ZDHHC9:118-155/364 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, May 2010].

Function:
The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS.

Subunit:
Interacts with GOLGA7.

Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.

Tissue Specificity:
Highly expressed in kidney, skeletal muscle, brain, lung and liver. Absent in thymus, spleen and leukocytes.

DISEASE:
Defects in ZDHHC9 are the cause of mental retardation syndromic X-linked ZDHHC9-related (MRXSZ) [MIM:300799]. A disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Some patients have marfanoid habitus as an additional feature.

Similarity:
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
Contains 1 DHHC-type zinc finger.

SWISS:
Q9Y397

Gene ID:
51114

Database links:

Entrez Gene: 51114 Human

Entrez Gene: 208884 Mouse

Entrez Gene: 302808 Rat

Omim: 300646 Human

SwissProt: Q9Y397 Human

SwissProt: P59268 Mouse

Unigene: 193566 Human

Unigene: 207367 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

















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