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α2纤溶酶色素上皮衍生因子抗体
  • 产品货号：
    BN41196R
  • 中文名称：
    α2纤溶酶色素上皮衍生因子抗体
  • 英文名称：
    Rabbit anti-Alpha 2 antiplasmin Polyclonal antibody

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    产品规格

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  • BN41196R-100ul

    100ul

    ¥2360.00

    交叉反应：Human,Mouse,Rat(predicted:Dog,Horse,Rabbit) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA

  • BN41196R-200ul

    200ul

    ¥3490.00

    交叉反应：Human,Mouse,Rat(predicted:Dog,Horse,Rabbit) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA

英文名称Alpha 2 antiplasmin
中文名称α2纤溶酶色素上皮衍生因子抗体
别    名A2AP; A2AP_HUMAN; AAP; Alpha 2 antiplasmin; Alpha 2 antiplasmin pigment epithelium derived factor; Alpha 2 AP; ALPHA 2 PI; Alpha 2 plasmin inhibitor; Alpha 2 plasmin inhibitor deficiency; Alpha-2-antiplasmin; Alpha-2-AP; Alpha-2-PI; Alpha-2-plasmin inhibitor; Antiplasmin deficiency; API; Plasmin inhibitor deficiency; PLI; Serine (or cysteine) peptidase inhibitor, clade F, member 2; Serine (Or cysteine) peptidase inhibitor, clade F, member 2, isoform CRA_c; Serine (or cysteine) proteinase inhibitor, clade F (alpha 2 antiplasmin pigment epithelium derived factor) member 2; Serine (Or cysteine) proteinase inhibitor, clade F, member 2; Serine or cysteine peptidase inhibitor clade F member 2; Serpin F2; Serpin peptidase inhibitor clade F; Serpin peptidase inhibitor, clade F (alpha 2 antiplasmin pigment epithelium derived factor) member 2; SERPINF2.  







研究领域心血管  细胞生物  免疫学  泛素  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,  (predicted: Dog, Horse, Rabbit, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量50kDa
细胞定位分泌型蛋白 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human SERPINF2:161-260/491 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Alpha 2 Antiplasmin is a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Function:
Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.

Subunit:
Forms protease inhibiting heterodimer with TMPRSS7.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed by the liver and secreted in plasma.

DISEASE:
Alpha-2-plasmin inhibitor deficiency (APLID) [MIM:262850]: An autosomal recessive disorder resulting in severe hemorrhagic diathesis. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the serpin family.

SWISS:
P08697

Gene ID:
5345

Database links:

Entrez Gene: 5345 Human

Omim: 613168 Human

SwissProt: P08697 Human

Unigene: 159509 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application














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