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蛋白质磷酸酶2A亚基3抗体
  • 产品货号:
    BN41167R
  • 中文名称:
    蛋白质磷酸酶2A亚基3抗体
  • 英文名称:
    Rabbit anti-PPP2R3 Polyclonal antibody
  • 货号

    产品规格

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  • BN41167R-100ul

    100ul

    ¥2360.00

    交叉反应:Mouse,Rat(predicted:Human,Dog,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

  • BN41167R-200ul

    200ul

    ¥3490.00

    交叉反应:Mouse,Rat(predicted:Human,Dog,Horse,Rabbit) 推荐应用:WB,IHC-P,IHC-F,IF,ELISA

英文名称PPP2R3
中文名称蛋白质磷酸酶2A亚基3抗体
别    名AI118493; DNA for thyroid hormone receptor binding site (258bp); P2R3A_HUMAN; PP2A subunit B B72/B130 isoforms; PP2A subunit B isoform PR72/PR130; PP2A subunit B isoform R3 isoform; PP2A subunit B isoforms B72/B130; PP2A subunit B PR72/PR130 isoforms; PP2A subunit B R3 isoform; Ppp2r3a; PR130; PR59; PR72; Serine/threonine protein phosphatase 2A 72/130 kDa regulatory subunit B; Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B.   
研究领域肿瘤  细胞生物  免疫学  信号转导  细胞周期蛋白  激酶和磷酸酶  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,  (predicted: Human, Dog, Horse, Rabbit, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量130kDa
细胞定位细胞核 细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human PPP2R3:801-900/1150 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

Function:
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

Subunit:
PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules.

Tissue Specificity:
Expressed in heart, brain, placenta, lung, muscle and kidney.

Similarity:
Contains 2 EF-hand domains.

SWISS:
Q06190

Gene ID:
5523

Database links:

Entrez Gene: 5523 Human

Omim: 604944 Human

SwissProt: Q06190 Human

Unigene: 518155 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.














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