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BN41138R-100ul
100ul
¥2360.00
交叉反应：Human,Mouse(predicted:Rat,Chicken,Dog,Pig,Cow,Horse) 推荐应用：IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
BN41138R-200ul
200ul
¥3490.00
交叉反应：Human,Mouse(predicted:Rat,Chicken,Dog,Pig,Cow,Horse) 推荐应用：IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
| 英文名称 | TRAK1 |
| 中文名称 | 驱动蛋白结合蛋白1抗体 |
| 别 名 | 106 kDa O-GlcNAc transferase-interacting protein; 106 kDa O GlcNAc transferase interacting protein; KIAA1042; OGT(O Glc NAc transferase) interacting protein 106 KDa; OIP106; TRAK1_HUMAN; Trafficking kinesin binding protein 1; Trafficking kinesin-binding protein 1; Trafficking protein kinesin binding 1; TRAK 1. |
| 研究领域 | 肿瘤 免疫学 信号转导 细胞骨架 肿瘤细胞生物标志物 线粒体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, ) |
| 产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 106kDa |
| 细胞定位 | 细胞核 细胞浆 线粒体 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TRAK1:171-270/953 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | The specific function of TRAK1 remains unknown. It interacts with O-GlcNAc transferase, RHOT1/Miro-1 and RHOT2/Miro-2. It shows high expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Function: Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors. Subunit: Interacts with O-GlcNAc transferase. Interacts with RHOT1/Miro-1 and RHOT2/Miro-2. Interacts with HGS. Interacts with GABRA1. Interacts with KIF5C. Subcellular Location: Cytoplasm. Nucleus. Mitochondrion. Early endosome. Endosome. Tissue Specificity: High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined. Post-translational modifications: O-glycosylated. Similarity: Contains 1 HAP1 N-terminal domain. SWISS: Q9UPV9 Gene ID: 22906 Database links: Entrez Gene: 22906 Human Omim: 608112 Human SwissProt: Q9UPV9 Human Unigene: 535711 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
