首页>>蛋白研究>>抗体>>纤维母细胞生长因子7抗体
纤维母细胞生长因子7抗体
  • 产品货号：
    BN40715R
  • 中文名称：
    纤维母细胞生长因子7抗体
  • 英文名称：
    Rabbit anti-KGF Polyclonal antibody

  • 货号

    产品规格

    售价

    备注

  • BN40715R-100ul

    100ul

    ¥2360.00

    交叉反应：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Rabbit) 推荐应用：WB

  • BN40715R-200ul

    200ul

    ¥3490.00

    交叉反应：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Rabbit) 推荐应用：WB

英文名称KGF
中文名称纤维母细胞生长因子7抗体
别    名FGF 7; FGF7; FGF-7; Fibroblast Growth Factor 7;HBGF 7; HBGF7; HBGF-7; Keratinocyte growth factor precursor; Heparin binding growth factor 7; Keratinocyte Growth Factor; FGF7_HUMAN; Heparin-binding growth factor 7.  
研究领域肿瘤  免疫学  信号转导  生长因子和激素  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, )
产品应用WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量18kDa
细胞定位分泌型蛋白 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human KGF:32-110/194 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍KGF is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

Function:
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation.

Subunit:
Interacts with FGFBP1. Interacts with FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.

Subcellular Location:
Secreted.

Tissue Specificity:
Epithelial cell.

Similarity:
Belongs to the heparin-binding growth factors family.

SWISS:
P21781

Gene ID:
2252

Database links:

Entrez Gene: 2252 Human

Entrez Gene: 14178 Mouse

Entrez Gene: 29348 Rat

Omim: 148180 Human

SwissProt: P21781 Human

SwissProt: P36363 Mouse

SwissProt: Q02195 Rat

Unigene: 567268 Human

Unigene: 330557 Mouse

Unigene: 98842 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

KGF/FGF7 (Fibroblast growth factor 7) 又称：HBGF-7 纤维母细胞生长因子7，是FGF家族的主要成员之一。 FGF家族参与细胞生长、组织修复、胚胎生长发育、组织器官的形成、肿瘤的生长和侵润等诸多生理病理功能。 成纤维细胞生长因子7的促增生作用主要来源于角化上皮细胞而不是间质细胞和内皮细胞，因此人们又称之为：角化上皮细胞生长因子（KGF）。

















image.png