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葡萄糖转运蛋白3抗体
  • 产品货号：
    BN40689R
  • 中文名称：
    葡萄糖转运蛋白3抗体
  • 英文名称：
    Rabbit anti-GLUT3 Polyclonal antibody

  • 货号

    产品规格

    售价

    备注

  • BN40689R-100ul

    100ul

    ¥2360.00

    交叉反应：Human,Mouse,Rat 推荐应用：WB

  • BN40689R-200ul

    200ul

    ¥3490.00

    交叉反应：Human,Mouse,Rat 推荐应用：WB

英文名称GLUT3
中文名称葡萄糖转运蛋白3抗体
别    名brain; facilitated glucose transporter member 3; Glucose Transporter GLUT3 ; FLJ90380; Glucose Transporter Type 3; Glucose transporter type 3 brain; GLUT 3; GLUT-3; GTR3_HUMAN; SLC2A3; Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 3; Solute carrier family 2.  
研究领域肿瘤  细胞生物  信号转导  新陈代谢  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, 
产品应用WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量54kDa
细胞定位细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human GLUT3 :401-496/496 <Cytoplasmic>
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍may act as a glucose transporter in neurons; may mediate increasd glucose uptake in response to neuronal injury. Glucose is fundamental to the metabolism of mammalian cells. Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response to insulin and IGF1 induced signaling. GLUT3 is detectable in a few normal cell type spermatids in testis with active spermatogenesis, placental trophoblast membranes, and neurons in brain. GLUT3 staining is also detectable in human cancers including those of the ovary, lung, and testis. Alternative names: FLJ90380; Glucose Transporter Type 3; Glucose transporter type 3 brain; GLUT 3; GLUT3; SLC2A3; Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 3.

Function:
Facilitative glucose transporter. Probably a neuronal glucose transporter.

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Melanosome.

Tissue Specificity:
Highly expressed in brain. Expressed in many tissues.

Similarity:
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

SWISS:
P11169

Gene ID:
6515

Database links:

Entrez Gene: 6515 Human

Entrez Gene: 20527 Mouse

Entrez Gene: 25551 Rat

Omim: 138170 Human

SwissProt: P11169 Human

SwissProt: P32037 Mouse

SwissProt: Q07647 Rat

Unigene: 419240 Human

Unigene: 395108 Mouse

Unigene: 95055 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

交换和转运（Trafficking and Transport） GLUT-3属于溶质运载蛋白家族成员（solute carrier family），主要功能是转载葡萄糖进入上皮细胞。 目前主要用于糖尿病肾病和视网膜病变的研究，也是肾小球系膜细胞上的主要葡萄糖转运体。GLUT3的功能状态直接影响系膜细胞的糖代谢及功能变化。 近期，研究人员也用来区别一些良、恶性肿瘤的鉴别。















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