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细胞色素P450Ⅱj3抗体
  • 产品货号：
    BN40662R
  • 中文名称：
    细胞色素P450Ⅱj3抗体
  • 英文名称：
    Rabbit anti-Cyp2J3 Polyclonal antibody

  • 货号

    产品规格

    售价

    备注

  • BN40662R-100ul

    100ul

    ¥2360.00

    交叉反应：Mouse,Rat 推荐应用：WB,IHC-P,IHC-F,IF,ELISA

  • BN40662R-200ul

    200ul

    ¥3490.00

    交叉反应：Mouse,Rat 推荐应用：WB,IHC-P,IHC-F,IF,ELISA

英文名称Cyp2J3
中文名称细胞色素P450Ⅱj3抗体
别    名cytochrome P450, family 2, subfamily j, polypeptide 3; Cyp2J3; cytochrome P450 monooxygenase; Cyp2j9; cytochrome P450, family 2, subfamily j, polypeptide 9; cytochrome P450, family 2, subfamily j, polypeptide 3; CYPIIJ3; cytochrome P450 2J3. 
研究领域心血管  细胞生物  免疫学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat, 
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量55kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from rat Cyp2-j3:401-502/502 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jan 2016].

Function:
This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation mainly to 14,15-, 11,12-, and 8,9-epoxyeicosatrienoic acids (EET). It also acts as an omega-1-hydroxylase by metabolizing arachidonic acid to 19-hydroxyeicosatetraenoic acid (19-OH-AA).

Subcellular Location:
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Tissue Specificity:
Abundantly expressed in heart and liver.

Similarity:
Belongs to the cytochrome P450 family.

SWISS:
P51589

Gene ID:
313375

Database links:

 



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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